5 Lipoxygenase Rabbit Polyclonal Antibody

Catalog number R1512-14

Price for R1512-14

Size / count 100 µL

About this product

5-lipoxygenase (5-LO) is expressed primarily in polymorphonuclear leukocytes, macrophages, and mast cells. 5-LO performs the first two catalytic reactions in the biosynthesis of leukotrienes, lipid metabolites that induce contractions of airway smooth muscle and increase vascular permeability during anaphylaxis. The cellular localization of 5-LO varies between cell types. In activated blood polymorphonuclear leukocytes 5-LO undergoes calcium dependent translocation from the cytosol to the nuclear envelope. In alveolar macrophages, the majority of 5-LO is localized in the nucleus and, upon activation of these cells, intranuclear 5-LO binds to the nuclear membrane. This intracellular shuttling of 5-LO is dependent on the association with various signaling molecules, phosphorylation and the presence of a distinct

Specifications

Catalog number: R1512-14
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: 5 LO antibody 5 LOX antibody 5-lipoxygenase antibody 5-LO antibody 5-LOX antibody 5LOX antibody 5LPG antibody ALOX 5 antibody Alox5 antibody Arachidonate 5 lipoxygenase antibody Arachidonate 5-lipoxygenase antibody arachidonic 5-lipoxygenase alpha-10 isoform antibody arachidonic 5-lipoxygenase delta-10-13 isoform antibody arachidonic 5-lipoxygenase delta-13 isoform antibody arachidonic 5-lipoxygenase delta-p10 isoform antibody Arachidonic acid 5 lipoxygenase antibody Leukotriene A4 synthase antibody LOG 5 antibody LOG5 antibody LOX5_HUMAN antibody MGC163204 antibody
Abbreviation: 5-LO, 5-lipoxygenase, ALOX5, LOG5
Swiss Prot: P09917 Human, P48999 Mouse, P12527 Rat
Cellular Locus: Cytoplasm, Membrane, Nucleus.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide within human 5 Lipoxygenase aa 121-165.
Isotype: IgG
Conjugation: Non-conjugated
Type: Rabbit polyclonal Antibody
Applications: WB
Positive Control: Hela cell lysate, Jurkat cell lysate.
Concentration: 1 mg/mL
Dilution: WB: 1:500-1:1,000
Purity: Immunogen affinity purified.
Form: Liquid
Buffer: 1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 78 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for 5 Lipoxygenase Rabbit Polyclonal Antibody?

The catalog number for 5 Lipoxygenase Rabbit Polyclonal Antibody is R1512-14.

What sizes are available for 5 Lipoxygenase Rabbit Polyclonal Antibody?

5 Lipoxygenase Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is 5 Lipoxygenase Rabbit Polyclonal Antibody in stock?

5 Lipoxygenase Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is 5 Lipoxygenase Rabbit Polyclonal Antibody used for?

What is the purity of this recombinant protein?

Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.