PLCG2 Rabbit Polyclonal Antibody — image 1 of 3

Product details

PLCG2 Rabbit Polyclonal Antibody

Catalog number R1512-4

Price for R1512-4

Size / count 100 µL

About this product

Phosphoinositide-specific phospholipase C (PLC) plays a critical role in the initiation of receptor mediated signal transduction through the generation of the two second messengers, inositol 1,4,5-triphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate.There are many mammalian PLC isozymes, including PLC β1, PLC β2, PLC β3, PLC β4, PLC γ1, PLC γ2, PLC δ1, PLC δ2 and PLC e. After stimulation of the collagen receptor glycoprotein VI in human platelets, PLC γ2 associates with several tyrosine-phosphorylated proteins (Syk, SLP-76, Lyn, linker for activation of T cells (LAT) and the FcR γ chain), which bind to its C-terminal SH2 domain. PLC γ1 associates with Syk in B cells, but PLC γ2 does not associate with Syk in platelets. The C-terminal SH2 domain is involved in the regulation of PLC γ2. In addition, Btk can induce PLC γ2 tyrosine phosphorylation and initiate calcium moblization in CD72-stimulated B lymphocytes.

Specifications

Catalog number: R1512-4
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: 1 phosphatidylinositol 4 5 bisphosphate phosphodiesterase gamma 2 antibody 1-phosphatidylinositol-4 antibody 5-bisphosphate phosphodiesterase gamma-2 antibody EC 3.1.4.11 antibody Phosphoinositide phospholipase C antibody Phosphoinositide phospholipase C-gamma-2 antibody Phospholipase C gamma 2 antibody Phospholipase C, gamma 2 (phosphatidylinositol specific) antibody Phospholipase C-gamma-2 antibody Phospholipase C-IV antibody PLC 2 antibody PLC gamma 2 antibody PLC IV antibody PLC-gamma-2 antibody PLC-IV antibody Plcg2 antibody PLCG2_HUMAN antibody
Abbreviation: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 Phosphoinositide phospholipase C-gamma-2 Phospholipase C-IV PLC-IV Phospholipase C-gamma-2 PLC-gamma-2
Swiss Prot: P16885 Human
Cellular Locus: Cytosol, Autolysosome.
Host: Rabbit
Species Reactivity: Human
Immunogen: Synthetic peptide within human PLCG2 aa 1200-1265.
Isotype: IgG
Conjugation: Non-conjugated
Type: Rabbit polyclonal Antibody
Applications: WB, IF-Cell, IHC-P, FC
Positive Control: Raji cell lysates, AGS, human tonsil tissue, Daudi.
Concentration: 1 mg/mL
Dilution: WB: 1:500-1:1,000;IF-Cell: 1:50-1:100;IHC-P: 1:100-1:400;FC: 1:50-1:100
Purity: Immunogen affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: 148 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for PLCG2 Rabbit Polyclonal Antibody?

The catalog number for PLCG2 Rabbit Polyclonal Antibody is R1512-4.

What sizes are available for PLCG2 Rabbit Polyclonal Antibody?

PLCG2 Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is PLCG2 Rabbit Polyclonal Antibody in stock?

PLCG2 Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is PLCG2 Rabbit Polyclonal Antibody used for?

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

Is this product classed as hazardous or restricted for shipping?

Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.

Can you help me confirm if this product is right for my specific experiment?

Yes, contact us with details of your sample type, species, and intended application, and our specialists will confirm suitability or suggest an alternative from our supplier network if this isn’t the best fit.