FBXL2 Rabbit Polyclonal Antibody — image 1 of 3

Product details

FBXL2 Rabbit Polyclonal Antibody

Catalog number R1706-15

Price for R1706-15

Size / count 100 µL

About this product

Calcium-activated substrate recognition component of a SCF (SKP1-cullin-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Unlike many F-box proteins, FBXL2 doesn't seem to target phosphodegron within its substrates but rather calmodulin-binding motifs. Targets PCYT1A for its monoubiquitination and degradation, this is antagonized by calmodulin (By similarity). Targets the cyclins CCND2 and CCND3 for polyubiquitination and degradation, leading to cell-cycle arrest in G (0), also antagonized by calmodulin. Binds to hepatitis C virus non-structural protein 5A (NS5A) in a reaction crucial for hepatitis C virus RNA replication.

Specifications

Catalog number: R1706-15
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: DKFZP564P0622 antibody F box and leucine rich repeat protein 2 antibody F box protein containing leucine rich repeats antibody F box protein FBL2/FBL3 antibody F box/LRR repeat protein 2 antibody F-box and leucine-rich repeat protein 2 antibody F-box protein FBL2/FBL3 antibody F-box/LRR-repeat protein 2 antibody FBL 2 antibody FBL 3 antibody FBL2 antibody FBL3 antibody FBXL 2 antibody FBXL2 antibody FBXL2_HUMAN antibody
Abbreviation: FBXL2, FBL2, FBL3
Swiss Prot: Q9UKC9 Human, Q8BH16 Mouse, F1M768 Rat
Cellular Locus: Membrane.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide corresponding to Human FBXL2 aa 51-100 / 423.
Isotype: IgG
Conjugation: Non-conjugated
Type: Rabbit polyclonal Antibody
Applications: WB, IF-Cell, IHC-P, FC
Positive Control: SiHa cell lysate, Mouse skeletal muscle tissue lysate, Rat skeletal muscle tissue lysate, A431, HUVEC, SiHa, human kidney tissue, mouse kidney tissue, rat kidney tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:1,000-1:10,000 ;IF-Cell: 1:50-1:200 ;IHC-P: 1:2,000 ;FC: 1:1,000
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 47 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for FBXL2 Rabbit Polyclonal Antibody?

The catalog number for FBXL2 Rabbit Polyclonal Antibody is R1706-15.

What sizes are available for FBXL2 Rabbit Polyclonal Antibody?

FBXL2 Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is FBXL2 Rabbit Polyclonal Antibody in stock?

FBXL2 Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is FBXL2 Rabbit Polyclonal Antibody used for?

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.