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Product details

Fatty Acid Synthase Rabbit Polyclonal Antibody

Catalog number R1706-8

Price for R1706-8

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Size / count 100 µL

About this product

Fatty acid biosynthesis is mediated by seven catalytic enzymes and an acyl carrier protein (ACP), to which various acyl intermediates are covalently attached. Fatty Acid Synthase (FAS) is the anabolic enzyme that contains the seven unique catalytic sites and mediates the conversion of acetyl-CoA and malonyl-CoA, in the presence of the cofactor NADPH, into long-chain saturated fatty acids, such as palmitate. Human Fatty Acid Synthase cDNA encodes a 2,504 amino acid protein. Catalytically active Fatty Acid Synthase is a homodimer. Human Fatty Acid Synthase mRNA is variably expressed with abundant levels present in brain, lung and liver. Fatty acid synthetic metabolism is abnormally elevated in tumor cells and may support cell growth or survival of malignant cancers.

Specifications

Catalog number
R1706-8
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Product Name Alternative
[Acyl-carrier-protein] S acetyltransferase antibody [Acyl-carrier-protein] S malonyltransferase antibody 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase antibody 3-oxoacyl-[acyl-carrier-protein] reductase antibody 3-oxoacyl-[acyl-carrier-protein] synthase antibody Enoyl-[acyl-carrier-protein] reductase antibody FAS antibody FAS_HUMAN antibody FASN antibody Fatty acid synthase antibody MGC14367 antibody MGC15706 antibody OA 519 antibody Oleoyl-[acyl-carrier-protein] hydrolase antibody SDR27X1 antibody Short chain dehydrogenase/reductase family 27X member 1 antibody
Abbreviation
FASN, FAS
Swiss Prot
P49327 Human, P19096 Mouse, P12785 Rat
Cellular Locus
Cytoplasm. Melanosome.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein within human Fatty Acid Synthase aa 801-1050.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IF-Cell, IHC-P
Positive Control
A549, MCF-7, Hela, human prostate tissue, human breast cancer tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:2,000;IF-Cell: 1:50-1:200;IHC-P: 1:50-1:200
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
273 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
No

Frequently Asked Questions

What is the catalog number for Fatty Acid Synthase Rabbit Polyclonal Antibody?

The catalog number for Fatty Acid Synthase Rabbit Polyclonal Antibody is R1706-8.

What sizes are available for Fatty Acid Synthase Rabbit Polyclonal Antibody?

Fatty Acid Synthase Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is Fatty Acid Synthase Rabbit Polyclonal Antibody in stock?

Fatty Acid Synthase Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is Fatty Acid Synthase Rabbit Polyclonal Antibody used for?

Fatty acid biosynthesis is mediated by seven catalytic enzymes and an acyl carrier protein (ACP), to which various acyl intermediates are covalently attached. Fatty Acid Synthase (FAS) is the anabolic enzyme that contains the seven unique catalytic sites and mediates the conversion of acetyl-CoA and

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.

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