Anti-Lamin B1 Antibody [SI17-07] — image 1 of 2

Product details

Anti-Lamin B1 Antibody [SI17-07]

Catalog number ET1606-27TR

Price for ET1606-27TR

Size / count 20 µL

About this product

A unique family of cysteine proteases has been described that differs in sequence, structure and substrate specificity from any previously described protease family. This family, termed Ced-3/ICE, functions as key components of the apoptotic machinery and act to destroy specific target proteins which are critical to cellular longevity. Nuclear lamins are critical to maintaining the integrity of the nuclear envelope and cellular morphology as components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. B-type lamins undergo a series of modifications, such as farnesylation and phosphorylation. Increased phosphorylation of the lamins occurs before envelope disintegration and probably plays a role in regulating lamin associations. Nuclear Lamin B is fragmented as a consequence of apoptosis by an unidentified member of the ICE family.

Specifications

Catalog number: ET1606-27TR
Size / count: 20 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: ADLD antibody lamin B1 antibody Lamin-B1 antibody LMN antibody LMN2 antibody LMNB antibody Lmnb1 antibody LMNB1_HUMAN antibody MGC111419 antibody OTTHUMP00000159218 antibody
Abbreviation: LMNB1
Swiss Prot: P20700 Human; P14733 Mouse; P70615 Rat
Cellular Locus: Nucleus inner membrane.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide within Human Lamin B1 aa 511-560 / 586.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IF-Tissue, IHC-P, CUT&Tag-seq
Positive Control: Hela cell lysate, Jurkat cell lysate, NIH/3T3 cell lysate, human liver tissue, human colon carcinoma tissue, human breast carcinoma tissue, mouse colon tissue, mouse brain tissue, PC-12 cell lysate, human lymph nodes tissue, mouse large intestine tissue, HepG2.
Concentration: 1 mg/mL
Dilution: WB: 1:1,000-1:5,000 ;IF-Tissue: 1:50-1:200 ;IHC-P: 1:500-1:1,000
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 66 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: True

Frequently Asked Questions

What is the catalog number for Anti-Lamin B1 Antibody [SI17-07]?

The catalog number for Anti-Lamin B1 Antibody [SI17-07] is ET1606-27TR.

What sizes are available for Anti-Lamin B1 Antibody [SI17-07]?

Anti-Lamin B1 Antibody [SI17-07] is available in the following size(s): 20 µL.

Is Anti-Lamin B1 Antibody [SI17-07] in stock?

Anti-Lamin B1 Antibody [SI17-07] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Anti-Lamin B1 Antibody [SI17-07] used for?

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.