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Product details

Anti-Integrin alpha V Antibody [SC56-07]

Catalog number ET1610-15TR

Price for ET1610-15TR

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Size / count 20 µL

About this product

Integrins are heterodimers composed of noncovalently associated transmembrane a and b subunits. The 16 a and 8 b subunits heterodimerize to produce more than 20 different receptors. Most integrin receptors bind ligands that are components of the extracellular matrix, including Fibronectin, collagen and vitronectin. Certain integrins can also bind to soluble ligands, such as fibrinogen, or to counterreceptors on adjacent cells such as the intracellular adhesion molecules (ICAMs), leading to aggregation of cells. Ligands serve to cross-link or cluster integrins by binding to adjacent integrin receptors; both receptor clustering and ligand occupancy are necessary for the activation of integrin-mediated responses. In addition to mediating cell adhesion and cytoskeletal organization, integrins function as signaling receptors. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis.

Specifications

Catalog number
ET1610-15TR
Size / count
20 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Product Name Alternative
CD51 antibody Integrin alpha-V light chain antibody integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) antibody Integrin, alpha V antibody Integrin, beta 6 antibody ITAV_HUMAN antibody ITGAV antibody ITGB6 antibody Vitronectin receptor subunit alpha antibody
Abbreviation
ITGAV, MSK8, VNRA, ITGB6
Swiss Prot
P06756 Human; P43406 Mouse
Cellular Locus
Membrane.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within of Human Integrin alpha V aa 1000-1048 / 1048.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IF-Cell, FC, IHC-P
Positive Control
A549 cell lysate, HeLa cell lysate, NIH/3T3 cell lysate, C6 cell lysate, rat heart tissue lysate, A549, SiHa, MCF-7, human placenta tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:5,000 ;IF-Cell: 1:50-1:100 ;FC: 1:50-1:100 ;IHC-P: 1:1,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 116 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
True

Frequently Asked Questions

What is the catalog number for Anti-Integrin alpha V Antibody [SC56-07]?

The catalog number for Anti-Integrin alpha V Antibody [SC56-07] is ET1610-15TR.

What sizes are available for Anti-Integrin alpha V Antibody [SC56-07]?

Anti-Integrin alpha V Antibody [SC56-07] is available in the following size(s): 20 µL.

Is Anti-Integrin alpha V Antibody [SC56-07] in stock?

Anti-Integrin alpha V Antibody [SC56-07] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Anti-Integrin alpha V Antibody [SC56-07] used for?

Integrins are heterodimers composed of noncovalently associated transmembrane a and b subunits. The 16 a and 8 b subunits heterodimerize to produce more than 20 different receptors. Most integrin receptors bind ligands that are components of the extracellular matrix, including Fibronectin, collagen

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.

Is there an additional fee for hazardous or dry ice shipping of this product?

Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

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