Anti-Caspase-9 Antibody [SC65-05]

Catalog number ET1610-95TR

Price for ET1610-95TR

Size / count 20 µL

About this product

Caspase-9 belongs to a family of caspases, cysteine-aspartic proteases involved in apoptosis and cytokine signalling. Apoptotic signals cause the release of cytochrome c from mitochondria and activation of apaf-1 (apoptosome), which then cleaves the pro-enzyme of caspase-9 into the active dimer form. Regulation of this enzyme occurs through phosphorylation by an allosteric inhibitor, inhibiting dimerization and inducing a conformational change. Correct caspase-9 function is required for apoptosis, leading to the normal development of the central nervous system. Caspase-9 has multiple additional cellular functions that are independent of its role in apoptosis. Nonapoptotic roles of caspase-9 include regulation of necroptosis, cellular differentiation, innate immune response, sensory neuron maturation, mitochondrial homeostasis, corticospinal circuit organization, and ischemic vascular injury.

Specifications

Catalog number: ET1610-95TR
Size / count: 20 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: Caspase9 APAF-3 antibody APAF3 antibody Apoptosis related cysteine peptidase antibody Apoptotic protease Mch-6 antibody Apoptotic protease-activating factor 3 antibody CASP-9 antibody CASP9 antibody CASP9_HUMAN antibody Caspase 9 apoptosis related cysteine peptidase antibody Caspase 9 Dominant Negative antibody Caspase 9c antibody Caspase-9 antibody Caspase-9 subunit p10 antibody ICE LAP6 antibody ICE like apoptotic protease 6 antibody ICE-LAP6 antibody ICE-like apoptotic protease 6 antibody MCH6 antibody PPP1R56 antibody protein phosphatase 1, regulatory subunit 56 antibody RNCASP9 antibody
Abbreviation: CASP-9, APAF-3, ICE-LAP6, CASP9
Swiss Prot: P55211 Human; Q8C3Q9 Mouse
Cellular Locus: Apoptosome, cytosol, Mitochondrion, nucleus, cytoplasm, protein-containing complex.
Host: Rabbit
Species Reactivity: Human, Mouse
Immunogen: Recombinant protein within Human Caspase-9 aa 95-335 / 416.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IP
Positive Control: C2C12 cell lysate, Hela cell lysate, Jurkat cell lysate.
Concentration: 1 mg/mL
Dilution: WB: 1:500-1:2,000 ;IP: Use at an assay dependent concentration.
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 46/30/17/37 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: True

Frequently Asked Questions

What is the catalog number for Anti-Caspase-9 Antibody [SC65-05]?

The catalog number for Anti-Caspase-9 Antibody [SC65-05] is ET1610-95TR.

What sizes are available for Anti-Caspase-9 Antibody [SC65-05]?

Anti-Caspase-9 Antibody [SC65-05] is available in the following size(s): 20 µL.

Is Anti-Caspase-9 Antibody [SC65-05] in stock?

Anti-Caspase-9 Antibody [SC65-05] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Anti-Caspase-9 Antibody [SC65-05] used for?

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.