Anti-IRF3 Antibody [SD2062] — image 1 of 2

Product details

Anti-IRF3 Antibody [SD2062]

Catalog number ET1612-14TR

Price for ET1612-14TR

Size / count 20 µL

About this product

Interferon regulatory factor-1 (IRF-1) and IRF-2 have been identified as novel DNA-binding factors that function as regulators of both type I interferon (interferon-α and β) and interferon-inducible genes. The two factors are structurally related, particularly in their N-terminal regions, which confer DNA binding specificity. In addition, both bind to the same sequence within the promoters of interferon-α and interferon-β genes. IRF-1 functions as an activator of interferon transcription, while IRF-2 binds to the same cis elements and represses IRF-1 action. IRF-1 and IRF-2 have been reported to act in a mutually antagonistic manner in regulating cell growth; overexpression of the repressor IRF-2 leads to cell transformation while concomitant overexpression of IRF-1 causes reversion. IRF-1 and IRF-2 are members of a larger family of DNA binding proteins that includes IRF-3, IRF-4, IRF-5, IRF-6, IRF-7, ISGF-3γ p48 and IFN consensus sequence-binding protein (ICSBP).

Specifications

Catalog number: ET1612-14TR
Size / count: 20 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: IIAE7 antibody Interferon regulatory factor 3 antibody IRF 3 antibody IRF-3 antibody IRF3 antibody IRF3_HUMAN antibody MGC94729 antibody
Abbreviation: IRF-3
Swiss Prot: Q14653 Human; P70671 Mouse
Cellular Locus: Cytoplasm, Nucleus.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide within Human IRF3 aa 71-120 / 427.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IF-Cell, IF-Tissue, IHC-P, FC
Positive Control: HeLa cell lysate, Jurkat cell lysate, MCF7 cell lysate, A549 cell lysate, THP-1 cell lysate, Hela, MCF-7, PANC-1, human breast carcinoma tissue, human kidney tissue, human pancreas tissue, human tonsil tissue, mouse spleen tissue, mouse kidney tissue, mouse pancreas tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:5,000 ;IF-Cell: 1:50-1:200 ;IF-Tissue: 1:50-1:200 ;IHC-P: 1:50-1:200 ;FC: 1:50-1:100
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 47 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: True

Frequently Asked Questions

What is the catalog number for Anti-IRF3 Antibody [SD2062]?

The catalog number for Anti-IRF3 Antibody [SD2062] is ET1612-14TR.

What sizes are available for Anti-IRF3 Antibody [SD2062]?

Anti-IRF3 Antibody [SD2062] is available in the following size(s): 20 µL.

Is Anti-IRF3 Antibody [SD2062] in stock?

Anti-IRF3 Antibody [SD2062] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Anti-IRF3 Antibody [SD2062] used for?

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.