Anti-pro Caspase-7 Antibody [SD20-57] — image 1 of 2

Product details

Anti-pro Caspase-7 Antibody [SD20-57]

Catalog number ET1612-28TR

Price for ET1612-28TR

Size / count 20 µL

About this product

A unique family of Cysteine proteases has been described that differs in sequence, structure and substrate specificity from any previously described protease family. This family, Ced-3/caspase-1, is comprised of caspase-1, caspase-2, caspase-3, caspase-4, caspase-6, caspase-7 (also designated Mch3, ICE-LAP3 or CMH-1), caspase-9 and caspase-10. Ced-3/caspase-1 family members function as key components of the apoptotic machinery and act to destroy specific target proteins which are critical to cellular longevity. Poly (ADP-ribose) polymerase plays an integral role in surveying for DNA mutations and double strand breaks. Caspase-3, caspase-7 and caspase-9, but not caspase-1, have been shown to cleave the nuclear protein PARP into an apoptotic fragment. Caspase-6, but not caspase-3, has been shown to cleave the nuclear lamins which are critical to maintaining the integrity of the nuclear envelope and cellular morphology. Caspase-10 has been shown to activate caspase-3 and caspase-7 in response to apoptotic stimuli.

Specifications

Catalog number: ET1612-28TR
Size / count: 20 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: Caspase7 apoptosis-related cysteine peptidase antibody Apoptotic protease Mch-3 antibody CASP-7 antibody CASP7 antibody CASP7_HUMAN antibody Caspase-7 subunit p11 antibody Caspase-7 antibody Caspase 7 antibody Caspase7 antibody CMH-1 antibody ICE-LAP3 antibody ICE-like apoptotic protease 3 antibody
Abbreviation: CASP-7, ICE-LAP3, CASP7
Swiss Prot: P55210 Human
Cellular Locus: Cytoplasm.
Host: Rabbit
Species Reactivity: Human
Immunogen: Synthetic peptide within Human Caspase 7 aa 1-50 / 303.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IF-Cell, IF-Tissue, IHC-P
Positive Control: Hela, HepG2, human liver tissue, human kidney tissue,human lung lysates.
Concentration: 1 mg/mL
Dilution: WB: 1:1,000-1:2,000;IF-Cell: 1:50-1:200;IF-Tissue: 1:50-1:200;IHC-P: 1:50-1:200
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: 34 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: True

Frequently Asked Questions

What is the catalog number for Anti-pro Caspase-7 Antibody [SD20-57]?

The catalog number for Anti-pro Caspase-7 Antibody [SD20-57] is ET1612-28TR.

What sizes are available for Anti-pro Caspase-7 Antibody [SD20-57]?

Anti-pro Caspase-7 Antibody [SD20-57] is available in the following size(s): 20 µL.

Is Anti-pro Caspase-7 Antibody [SD20-57] in stock?

Anti-pro Caspase-7 Antibody [SD20-57] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Anti-pro Caspase-7 Antibody [SD20-57] used for?

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.