Anti-LYVE1 Antibody [JF0979] — image 1 of 2

Product details

Anti-LYVE1 Antibody [JF0979]

Catalog number ET1702-29TR

Price for ET1702-29TR

Size / count 20 µL

About this product

Lymphatic vessel endothelial hyaluronan receptor-1 (LYVE-1) is expressed on the cell surface as a protein that is reduced by glycosidase treatment. LYVE-1 is abundant in spleen, lymph node, heart, lung and fetal liver, and is less abundant in appendix, bone marrow, placenta, muscle and adult liver. Expression of LYVE-1 is largely restricted to endothelial cells lining lymphatic vessels and splenic sinusoidal endothelial cells. LYVE-1 binds to both soluble and immobilized hyaluronan (HA) with greater specificity than HCAM. Like HCAM, the LYVE-1 molecule binds both soluble and immobilized HA. However, unlike HCAM, the LYVE-1 molecule co-localizes with HA on the luminal face of the lymph vessel wall and is completely absent from blood vessels. Hence, LYVE-1 is the first lymph-specific HA receptor to be characterized and is a uniquely powerful marker for lymph vessels themselves. LYVE-1 is used as a marker to study tumor lymphangiogenesis, which is an important area of investigation.

Specifications

Catalog number: ET1702-29TR
Size / count: 20 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: Cell surface retention sequence-binding protein 1 antibody CRSBP 1 antibody CRSBP-1 antibody CRSBP1 antibody extracellular link domain containing 1 antibody extracellular link domain-containing 1 antibody Extracellular link domain-containing protein 1 antibody HAR antibody Hyaluronic acid receptor antibody Lymphatic endothelium specific hyaluronan receptor antibody lymphatic vessel endothelial hyaluronan receptor 1 antibody Lymphatic vessel endothelial hyaluronic acid receptor 1 antibody LYVE 1 antibody LYVE-1 antibody LYVE1 antibody LYVE1_HUMAN antibody XLKD1 antibody
Abbreviation: LYVE-1, CRSBP-1, LYVE1
Swiss Prot: Q9Y5Y7 Human
Cellular Locus: Membrane.
Host: Rabbit
Species Reactivity: Human
Immunogen: Synthetic peptide within Human LYVE1 aa 36-72 / 322.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IF-Tissue, IHC-P, FC
Positive Control: MCF-7 cell lysate, SW480 cell lysate, A431 cell lysate, HUVEC cell lysate, A431, HUVEC, SW480, human spleen tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:500-1:2,000 ;IF-Tissue: 1:50-1:200 ;IHC-P: 1:50-1:200 ;FC: 1:50-1:100
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 35 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: True

Frequently Asked Questions

What is the catalog number for Anti-LYVE1 Antibody [JF0979]?

The catalog number for Anti-LYVE1 Antibody [JF0979] is ET1702-29TR.

What sizes are available for Anti-LYVE1 Antibody [JF0979]?

Anti-LYVE1 Antibody [JF0979] is available in the following size(s): 20 µL.

Is Anti-LYVE1 Antibody [JF0979] in stock?

Anti-LYVE1 Antibody [JF0979] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Anti-LYVE1 Antibody [JF0979] used for?

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.