Anti-FGFR3 Antibody [JM110-33] — image 1 of 2

Product details

Anti-FGFR3 Antibody [JM110-33]

Catalog number ET1703-65TR

Price for ET1703-65TR

Size / count 20 µL

About this product

Acidic and basic fibroblast growth factors (FGFs) are members of a family of multifunctional polypeptide growth factors that stimulate proliferation of cells of mesenchymal, epithelial and neuroectodermal origin. Like other growth factors, FGFs act by binding and activating specific cell surface receptors. These include the Flg receptor or FGFR-1, the Bek receptor or FGFR-2, FGFR-3, FGFR-4, FGFR-5 and FGFR-6. These receptors usually contain an extracellular ligand-binding region containing three immunoglobulin-like domains, a transmembrane domain and a cytoplasmic tyrosine kinase domain. The gene encoding human FGFR-3 maps to chromosome 4p16 and is alternatively spliced to produce three isoforms that are expressed in brain, kidney and testis. Defects in FGFR-3 are associated with several diseases, including Crouzon syndrome, achondroplasia, thanatophoric dysplasia, craniosynostosis adelaide type and hypochondroplasia. Mutations in FGFR-3 are also a cause of some bladder and cervical cancers.

Specifications

Catalog number: ET1703-65TR
Size / count: 20 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: ACH antibody CD 333 antibody CD333 antibody CD333 antigen antibody CEK 2 antibody CEK2 antibody FGFR 3 antibody FGFR-3 antibody FGFR3 antibody FGFR3_HUMAN antibody Fibroblast growth factor receptor 3 (achondroplasia thanatophoric dwarfism) antibody Fibroblast growth factor receptor 3 antibody Heparin binding growth factor receptor antibody HSFGFR3EX antibody Hydroxyaryl protein kinase antibody JTK 4 antibody JTK4 antibody MFR 3 antibody SAM 3 antibody Tyrosine kinase JTK 4 antibody Tyrosine kinase JTK4 antibody Z FGFR 3 antibody
Abbreviation: FGFR-3, FGFR3
Swiss Prot: P22607 Human; Q61851 Mouse
Cellular Locus: Cell membrane, Endoplasmic reticulum, Cytoplasmic vesicle, Secreted.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide within Human FGFR3 aa 30-63 / 806.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IF-Cell, IF-Tissue, IHC-P
Positive Control: Hela cell lysate, 293 cell lysate, MCF-7 cell lysate, HepG2 cell lysate, Rat skin tissue lysates, Mouse hippocampus lysates, MCF-7, HepG2, SH-SY5Y, human kidney tissue, mouse testis tissue, mouse kidney tissue, mouse brain tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:1,000 ;IF-Cell: 1:50-1:200 ;IF-Tissue: 1:50-1:200 ;IHC-P: 1:50-1:200
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 88 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: True

Frequently Asked Questions

What is the catalog number for Anti-FGFR3 Antibody [JM110-33]?

The catalog number for Anti-FGFR3 Antibody [JM110-33] is ET1703-65TR.

What sizes are available for Anti-FGFR3 Antibody [JM110-33]?

Anti-FGFR3 Antibody [JM110-33] is available in the following size(s): 20 µL.

Is Anti-FGFR3 Antibody [JM110-33] in stock?

Anti-FGFR3 Antibody [JM110-33] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Anti-FGFR3 Antibody [JM110-33] used for?

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.