Anti-FAP Antibody [JA56-11] — image 1 of 2

Product details

Anti-FAP Antibody [JA56-11]

Catalog number ET1704-23TR

Price for ET1704-23TR

Size / count 20 µL

About this product

FAP (fibroblast activation protein) is a cell surface glycoprotein and serine protease that is expressed primarily in fetal mesenchymal tissues and epithelial cancer fibroblasts. In cancer, FAP functions to promote cellular proliferation. In embryonic development, FAP functions to remodel developing tissues. FAP acts as an integral membrane gelatinase composed of N-glycosylated proteolytically inactive subunits. FAP expression on chondrocyte membranes is upregulated by the combination of the cytokines IL-1 and OSM and has been shown to increase in osteoarthritic patients. This expression is co-localized with MMP-1and MMP-13 as well as CD44 (variants v3 and v7/8). Mice that lack all copies of the FAP gene have been found to be fertile and to have developmental defects or change in cancer susceptibility.

Specifications

Catalog number: ET1704-23TR
Size / count: 20 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: 170 kDa melanoma membrane bound gelatinase antibody 170 kDa melanoma membrane-bound gelatinase antibody DPPIV antibody FAP antibody FAPA antibody Fibroblast activation protein alpha antibody Integral membrane serine protease antibody SEPR_HUMAN antibody Seprase antibody
Abbreviation: FAPalpha, SIMP, Seprase, FAP
Swiss Prot: Q12884 Human
Cellular Locus: Cell membrane. Cell surface.
Host: Rabbit
Species Reactivity: Human
Immunogen: Recombinant protein within Human FAP1 aa 1-160 / 760.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IHC-P, mIHC
Positive Control: Hela cell lysates, human colon carcinoma tissue, human pancreatic carcinoma.
Concentration: 1 mg/mL
Dilution: WB: 1:500-1:1,000 ;IHC-P: 1:50-1:200 ;mIHC: 1:3,000
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: 88 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: True

Frequently Asked Questions

What is the catalog number for Anti-FAP Antibody [JA56-11]?

The catalog number for Anti-FAP Antibody [JA56-11] is ET1704-23TR.

What sizes are available for Anti-FAP Antibody [JA56-11]?

Anti-FAP Antibody [JA56-11] is available in the following size(s): 20 µL.

Is Anti-FAP Antibody [JA56-11] in stock?

Anti-FAP Antibody [JA56-11] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Anti-FAP Antibody [JA56-11] used for?

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.