Anti-Glucose Transporter GLUT3 Antibody [JA50-31]

About this product

Glucose is fundamental to the metabolism of mammalian cells. Its passage across cell membranes is mediated by a family of transporters termed glucose transporters or Gluts. Glut1, Glut3 and Glut4 are high-affinity transporters, whereas Glut2 is a low-affinity transporter. In adipose and muscle tissue, Insulin stimulates a rapid and dramatic increase in glucose uptake, largely due to the redistribution of the Insulin-inducible glucose transporter, Glut4. In response to Insulin, Glut4 is quickly shuttled from an intracellular storage site to the plasma membrane, where it binds glucose. In contrast, the ubiquitously expressed glucose transporter Glut1 is constitutively targeted to the plasma membrane and shows a much less dramatic translocation in response to Insulin. Glut2 expression is seen in pancreatic b cells, hepatocytes and basolateral membranes of intestinal and epithelial cells, while the highest expression of Glut3 has been found in neuronal tissue.

Specifications

Catalog number

ET1704-59TR

Size / count

20 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9007-83-4

Product Name Alternative

brain antibody FLJ90380 antibody Glucose transporter type 3 antibody Glucose transporter type 3 brain antibody GLUT 3 antibody GLUT-3 antibody GLUT3 antibody GTR3_HUMAN antibody Slc2a3 antibody Solute Carrier Family 2 (Facilitated Glucose Transporter) Member 3 antibody Solute carrier family 2, facilitated glucose transporter member 3 antibody

Abbreviation

GLUT-3, SLC2A3, GLUT3

Swiss Prot

P11169 Human; P32037 Mouse; Q07647 Rat

Cellular Locus

Cell membrane. Perikaryon. Cell projection.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide within Human GLUT3 aa 11-60 / 496.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IHC-P, FC

Positive Control

HepG2 cell lysate, RAW264.7 cell lysate, C6 cell lysate, mouse brain tissue lysate, rat brain tissue lysate, human brain tissue, human embryo tissue, mouse brain tissue, SH-SY5Y.

Concentration

1 mg/mL

Dilution

WB: 1:5,000 ;IHC-P: 1:50-1:200 ;FC: 1:50-1:100

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 54 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

True