Anti-CD31 Antibody [7-A1]

About this product

Cell adhesion molecules are a family of closely related cell surface glycoproteins involved in cell-cell interactions during growth and are thought to play an important role in embryogenesis and development. Neuronal cell adhesion molecule (NCAM) expression is observed in a variety of human tumors including neuroblastomas, rhabdomyosarcomas, Wilms’ tumors, Ewing’s sarcomas and some primitive myeloid malignancies. The intracellular adhesion molecule-1 (ICAM-1), also referred to as CD54, is an integral membrane protein of the immunoglobulin superfamily. PECAM-1 (platelet/endothelial cell adhesion molecule-1), also referred to as CD31, is a glycoprotein expressed on the cell surfaces of monocytes, neutrophils, platelets and a subpopulation of T cells. VCAM-1 (vascular cell adhesion molecule-1) was first identified as an adhesion molecule induced on human endothelial cells by inflammatory cytokines such as IL-1, tumor necrosis factor (TNF) and lipopolysaccharide (LPS). The KALIG gene encodes a nerve cell adhesion molecule (NCAM)-like protein and is deleted in 66% of patients with Kallmann’s syndrome, anosmia with secondary hypogonadism.

Specifications

Catalog number

M1511-8TR

Size / count

20 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9007-83-4

Product Name Alternative

Adhesion molecule antibody CD31 antibody CD31 antigen antibody CD31 EndoCAM antibody EndoCAM antibody FLJ34100 antibody FLJ58394 antibody GPIIA antibody GPIIA' antibody PECA1 antibody PECA1_HUMAN antibody Pecam 1 antibody PECAM 1 CD31 EndoCAM antibody PECAM antibody PECAM-1 antibody Pecam1 antibody Platelet and endothelial cell adhesion molecule 1 antibody Platelet endothelial cell adhesion molecule antibody Platelet/endothelial cell adhesion molecule 1 antibody

Abbreviation

PECAM-1

Swiss Prot

P16284 Human

Cellular Locus

Cell junction. Cell membrane. Membrane.

Host

Mouse

Species Reactivity

Human

Immunogen

Synthetic peptide (KLH-coupled) within C-terminal residues of human CD31.

Isotype

IgG2a

Conjugation

Non-conjugated

Type

Mouse monoclonal Antibody

Applications

WB, IF-Cell, IF-Tissue, IHC-P, FC, mIHC

Positive Control

THP-1 cell lysate, Jurkat cell lysate, U-937 cell lysate, THP-1, human appendix tissue, human placenta tissue, human uterus tissue, human striated muscle tissue, human kidney tissue, human liver tissue, human stomach cancer tissue, human pancreatic carcinoma, Jurkat.

Concentration

2 mg/mL

Dilution

WB: 1:1,000-1:5,000 ;IF-Cell: 1:50-1:200 ;IF-Tissue: 1:50-1:200 ;IHC-P: 1:500-1:2,000 ;FC:1:50-1:100 ;mIHC: 1:1,000-1:3,000

Purity

Immunogen affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 83 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

False