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Product details

Phospho-Glucose Transporter GLUT4 (S488) Recombinant Rabbit Monoclonal Antibody [JE43-23]

Catalog number HA721866

Price for HA721866

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Size / count 100 µL

About this product

Glucose transporter type 4 (GLUT4), also known as solute carrier family 2, facilitated glucose transporter member 4, is a protein encoded, in humans, by the SLC2A4 gene. GLUT4 is the insulin-regulated glucose transporter found primarily in adipose tissues and striated muscle (skeletal and cardiac). The first evidence for this distinct glucose transport protein was provided by David James in 1988. The gene that encodes GLUT4 was cloned and mapped in 1989. At the cell surface, GLUT4 permits the facilitated diffusion of circulating glucose down its concentration gradient into muscle and fat cells. Once within cells, glucose is rapidly phosphorylated by glucokinase in the liver and hexokinase in other tissues to form glucose-6-phosphate, which then enters glycolysis or is polymerized into glycogen. Glucose-6-phosphate cannot diffuse back out of cells, which also serves to maintain the concentration gradient for glucose to passively enter cells.

Specifications

Catalog number
HA721866
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
Glucose transporter GLUT 4 Glucose transporter type 4 Glucose transporter type 4 insulin responsive GLUT 4 GLUT-4 GLUT4 GTR4_HUMAN Insulin responsive glucose transporter type 4 insulin-responsive kug SLC 2A4 SLC2A4 solute carrier family 2 (facilitated glucose transporter) member 4 Solute carrier family 2 member 4 Solute carrier family 2, facilitated glucose transporter member 4
Abbreviation
SLC2A4, GLUT4, GLUT-4
Swiss Prot
P14672 Human, P14142 Mouse, P19357 Rat
Cellular Locus
Cell membrane, Endomembrane system, Cytoplasm, perinuclear region.
Host
Rabbit
Species Reactivity
Mouse, Human, Rat
Immunogen
Synthetic phosphopeptide corresponding to residues surrounding Ser488 of Glucose Transporter GLUT4.
Isotype
IgG
Clone
JE43-23
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB
Positive Control
Mouse heart tissue lysates (no heat).
Concentration
1 mg/mL
Dilution
WB: 1:1,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 55 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for Phospho-Glucose Transporter GLUT4 (S488) Recombinant Rabbit Monoclonal Antibody [JE43-23]?

The catalog number for Phospho-Glucose Transporter GLUT4 (S488) Recombinant Rabbit Monoclonal Antibody [JE43-23] is HA721866.

What sizes are available for Phospho-Glucose Transporter GLUT4 (S488) Recombinant Rabbit Monoclonal Antibody [JE43-23]?

Phospho-Glucose Transporter GLUT4 (S488) Recombinant Rabbit Monoclonal Antibody [JE43-23] is available in the following size(s): 100 µL.

Is Phospho-Glucose Transporter GLUT4 (S488) Recombinant Rabbit Monoclonal Antibody [JE43-23] in stock?

Phospho-Glucose Transporter GLUT4 (S488) Recombinant Rabbit Monoclonal Antibody [JE43-23] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Phospho-Glucose Transporter GLUT4 (S488) Recombinant Rabbit Monoclonal Antibody [JE43-23] used for?

Glucose transporter type 4 (GLUT4), also known as solute carrier family 2, facilitated glucose transporter member 4, is a protein encoded, in humans, by the SLC2A4 gene. GLUT4 is the insulin-regulated glucose transporter found primarily in adipose tissues and striated muscle (skeletal and cardiac).

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

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