Human CD33 Recombinant Rabbit Monoclonal Antibody [PSH05-25] - BSA and Azide free (Capture)

Catalog number HA722254

Price for HA722254

Size / count 100 µL

About this product

CD33 or Siglec-3 (sialic acid binding Ig-like lectin 3, SIGLEC3, SIGLEC-3, gp67, p67) is a transmembrane receptor expressed on cells of myeloid lineage. It is usually considered myeloid-specific, but it can also be found on some lymphoid cells. It binds sialic acids, therefore is a member of the SIGLEC family of lectins. CD33 can be stimulated by any molecule with sialic acid residues such as glycoproteins or glycolipids. Upon binding, the immunoreceptor tyrosine-based inhibition motif (ITIM) of CD33, present on the cytosolic portion of the protein, is phosphorylated and acts as a docking site for Src homology 2 (SH2) domain-containing proteins like SHP phosphatases. This results in a cascade that inhibits phagocytosis in the cell.

Specifications

Catalog number: HA722254
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: CD 33 antibody CD33 antibody CD33 antigen (gp67) antibody CD33 antigen antibody CD33 molecule antibody CD33_HUMAN antibody FLJ00391 antibody gp67 antibody My9 antibody Myeloid cell surface antigen CD33 antibody Myeloid cell surface antigen CD33 precursor antibody Myeloid differentiation antigen CD33 antibody p67 antibody Sialic acid binding Ig like lectin 3 antibody Sialic acid binding immunoglobulin like lectin 3 antibody Sialic acid-binding Ig-like lectin 3 antibody SIGLEC 3 antibody Siglec-3 antibody SIGLEC3 antibody
Abbreviation: CD33, SIGLEC3
Swiss Prot: P20138 Human
Cellular Locus: Cell membrane; Peroxisome.
Host: Rabbit
Species Reactivity: Human
Immunogen: Recombinant protein within human CD33 aa 18-259 (P20138).
Isotype: IgG
Clone: PSH05-25
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: ELISA (Cap)
Positive Control: Recombinant Human CD33 protein.
Concentration: 1 mg/mL
Dilution: ELISA (Cap): Use at an assay dependent concentration. Can be paired for Sandwich ELISA with Rabbit monoclonal [PSH05-26] to Human CD33 (Detector) (HA722255). The reference range value is 22.6-5500pg/ml.
Purity: Protein A affinity purified.
Form: Liquid
Buffer: PBS (pH7.4).
Molecular Weight: Predicted band size: 40 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for Human CD33 Recombinant Rabbit Monoclonal Antibody [PSH05-25] - BSA and Azide free (Capture)?

The catalog number for Human CD33 Recombinant Rabbit Monoclonal Antibody [PSH05-25] - BSA and Azide free (Capture) is HA722254.

What sizes are available for Human CD33 Recombinant Rabbit Monoclonal Antibody [PSH05-25] - BSA and Azide free (Capture)?

Human CD33 Recombinant Rabbit Monoclonal Antibody [PSH05-25] - BSA and Azide free (Capture) is available in the following size(s): 100 µL.

Is Human CD33 Recombinant Rabbit Monoclonal Antibody [PSH05-25] - BSA and Azide free (Capture) in stock?

Human CD33 Recombinant Rabbit Monoclonal Antibody [PSH05-25] - BSA and Azide free (Capture) is currently made to order / not held in immediate stock. Contact us for lead time.

What is Human CD33 Recombinant Rabbit Monoclonal Antibody [PSH05-25] - BSA and Azide free (Capture) used for?

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.