GST3 Recombinant Mouse Monoclonal Antibody [11D5-R]

About this product

Glutathione S-transferases (GSTs) are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, the soluble GSTs are categorized into 4 main classes: alpha, mu, pi, and theta. This GST family member is a polymorphic gene encoding active, functionally different GSTP1 variant proteins that are thought to function in xenobiotic metabolism and play a role in susceptibility to cancer, and other diseases. In response to oxidative stress, upregulation of the GST family member GSTP1 occurs, consistent with this function. Furthermore, the GSTP1 gene is subject to CpG island hypermethylation, a state that correlates with human prostatic carcinogenesis. GSTP1 gene hypermethylation can be detected in urine, ejaculate and plasma from men with prostate cancer, potentially making GSTP1 a useful biomarker for prostate cancer screening.

Specifications

Catalog number

HA601272

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

Deafness antibody Deafness X-linked 7 antibody DFN7 antibody FAEES3 antibody Fatty Acid Ethyl Ester Synthase III antibody Glutathione S Transferase 3 antibody Glutathione S Transferase Pi antibody Glutathione S-transferase P antibody Glutathione S-transferase pi 1 antibody GST class-pi antibody GST3 antibody GSTP antibody Gstp1 antibody GSTP1-1 antibody GSTP1_HUMAN antibody PI antibody X linked 7 antibody

Abbreviation

GST class-pi, GSTP1-1

Swiss Prot

P09211 Human

Cellular Locus

Nucleus, Cytoplasm, Mitochondrion.

Host

Mouse

Species Reactivity

Human

Immunogen

Recombinant protein within Human GST3 aa 1-183 / 210.

Isotype

IgG1

Clone

11D5-R

Conjugation

Non-conjugated

Type

Recombinant Mouse monoclonal Antibody

Applications

WB, IF-Cell, IHC-P

Positive Control

HeLa cell lysate, HEK-293 cell lysate, MDA-MB-231 cell lysate, HT-29 cell lysate, Jurkat cell lysate, K-562 cell lysate, JAR cell lysate, human brain tissue lysate, human lung tissue lysate, HT-29, human testis tissue, human kidney tissue, human lung cancer tissue.

Concentration

1 mg/mL

Dilution

WB: 1:2,000 ;IF-Cell: 1:100 ;IHC-P: 1:5,000

Purity

Protein A affinity purified.

Form

Liquid

Buffer

PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 23 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes