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Product details

One-step TUNEL In Situ Apoptosis Kit (Green, Elab Fluor® 488)

Catalog number E-CK-A321-01

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Price for E-CK-A321-01

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Size / count 20 Assays

Specifications

Catalog number
E-CK-A321-01
Size / count
20 Assays
Dry ice
No
Hazardous
No
Discontinued
No
Detection Method
Fluorometric method
Assay Principle
When cells undergo apoptosis, specific DNA endonucleases will be activated, cutting the genomic DNA between the nucleosomes. The DNA of apoptotic cells is cleaved into multimers of 180~200bp fragments, corresponding to the oligonucleosomal size. Therefore, the DNA of apoptotic cells typically migrates as a ladder of 180~200bp on an agarose gel. The exposed 3'-OH of the broken DNA can be catalyzed by Terminal Deoxynucleotidyl Transferase (TdT) with fluorescein labeled dUTP, which can be detected with fluorescence microscope.
Sample Type
Paraffin section; frozen section; cell slide
Shipping Conditions
Ice bag
Storage Conditions
This product can be stored at -20°C for 12 months with shading light.
Citation 01
https://www.cell.com/cell/pdf/S0092-8674(23)01176-5.pdf
Citation 02
https://www.sciencedirect.com/science/article/pii/S2452199X24005309
Citation 03
https://www.nature.com/articles/s41467-023-42972-2
Citation 04
https://advanced.onlinelibrary.wiley.com/doi/abs/10.1002/advs.202417605
Citation 05
https://www.nature.com/articles/s41467-025-58805-3
Citation 06
https://onlinelibrary.wiley.com/doi/abs/10.1002/agt2.70086
Citation 07
https://www.sciencedirect.com/science/article/pii/S1385894724042232
Citation 08
https://www.tandfonline.com/doi/abs/10.1080/19490976.2025.2489072
Citation 09
https://link.springer.com/article/10.1186/s40824-023-00377-8
Citation 10
https://link.springer.com/article/10.1186/s12951-024-02735-7
Citation 11
https://www.sciencedirect.com/science/article/pii/S1043661824005012
Citation 12
https://www.sciencedirect.com/science/article/pii/S004896972404508X
Detection Instrument
Fluorescence Microscope

Frequently Asked Questions

What is the catalog number for One-step TUNEL In Situ Apoptosis Kit (Green, Elab Fluor® 488)?

The catalog number for One-step TUNEL In Situ Apoptosis Kit (Green, Elab Fluor® 488) is E-CK-A321.

What sizes are available for One-step TUNEL In Situ Apoptosis Kit (Green, Elab Fluor® 488)?

One-step TUNEL In Situ Apoptosis Kit (Green, Elab Fluor® 488) is available in the following size(s): 20 Assays, 50 Assays, 100 Assays.

How many pack sizes does One-step TUNEL In Situ Apoptosis Kit (Green, Elab Fluor® 488) come in?

One-step TUNEL In Situ Apoptosis Kit (Green, Elab Fluor® 488) is available in 3 different pack sizes.

Is One-step TUNEL In Situ Apoptosis Kit (Green, Elab Fluor® 488) in stock?

One-step TUNEL In Situ Apoptosis Kit (Green, Elab Fluor® 488) is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures One-step TUNEL In Situ Apoptosis Kit (Green, Elab Fluor® 488)?

One-step TUNEL In Situ Apoptosis Kit (Green, Elab Fluor® 488) is manufactured by Elabscience.

What is the estimated delivery time for One-step TUNEL In Situ Apoptosis Kit (Green, Elab Fluor® 488)?

Estimated delivery time for One-step TUNEL In Situ Apoptosis Kit (Green, Elab Fluor® 488) is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for One-step TUNEL In Situ Apoptosis Kit (Green, Elab Fluor® 488)?

The safety data sheet for One-step TUNEL In Situ Apoptosis Kit (Green, Elab Fluor® 488) is available here: https://789.bio/eb/mjPCGG.

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.

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