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Product details

One-step TUNEL In Situ Apoptosis Kit (Red, Elab Fluor® 555)

Catalog number E-CK-A325-01

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Price for E-CK-A325-01

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Size / count 20 Assays

Specifications

Catalog number
E-CK-A325-01
Size / count
20 Assays
Dry ice
No
Hazardous
No
Discontinued
No
Detection Method
Fluorometric method
Assay Principle
When cells undergo apoptosis, specific DNA endonucleases will be activated, cutting the genomic DNA between the nucleosomes. The DNA of apoptotic cells is cleaved into multimers of 180~200bp fragments, corresponding to the oligonucleosomal size. Therefore, the DNA of apoptotic cells typically migrates as a ladder of 180~200bp on an agarose gel. The exposed 3'-OH of the broken DNA can be catalyzed by Terminal Deoxynucleotidyl Transferase (TdT) with fluorescein labeled dUTP, which can be detected with fluorescence microscope.
Sample Type
Paraffin section; frozen section; cell slide
Shipping Conditions
Ice bag
Storage Conditions
This product can be stored at -20°C for 12 months with shading light.
Citation 01
https://www.science.org/doi/abs/10.1126/sciimmunol.adc9081
Citation 02
https://aacrjournals.org/cancerres/article/doi/10.1158/0008-5472.CAN-23-2491/735128
Citation 03
https://www.nature.com/articles/s41401-023-01218-z
Citation 04
https://biosignaling.biomedcentral.com/articles/10.1186/s12964-024-01479-z
Citation 05
https://www.ahajournals.org/doi/abs/10.1161/ATVBAHA.123.319119
Citation 06
https://www.nature.com/articles/s41420-023-01740-3
Citation 07
https://www.sciencedirect.com/science/article/pii/S0891584924011298
Citation 08
https://onlinelibrary.wiley.com/doi/abs/10.1002/glia.24449
Citation 09
https://pmc.ncbi.nlm.nih.gov/articles/PMC12147254/
Citation 10
https://journals.physiology.org/doi/abs/10.1152/ajpcell.00348.2023
Citation 11
https://www.mdpi.com/1422-0067/24/13/11210
Citation 12
https://www.sciencedirect.com/science/article/pii/S1567576924000158
Detection Instrument
Fluorescence Microscope

Frequently Asked Questions

What is the catalog number for One-step TUNEL In Situ Apoptosis Kit (Red, Elab Fluor® 555)?

The catalog number for One-step TUNEL In Situ Apoptosis Kit (Red, Elab Fluor® 555) is E-CK-A325.

What sizes are available for One-step TUNEL In Situ Apoptosis Kit (Red, Elab Fluor® 555)?

One-step TUNEL In Situ Apoptosis Kit (Red, Elab Fluor® 555) is available in the following size(s): 20 Assays, 100 Assays.

How many pack sizes does One-step TUNEL In Situ Apoptosis Kit (Red, Elab Fluor® 555) come in?

One-step TUNEL In Situ Apoptosis Kit (Red, Elab Fluor® 555) is available in 2 different pack sizes.

Is One-step TUNEL In Situ Apoptosis Kit (Red, Elab Fluor® 555) in stock?

One-step TUNEL In Situ Apoptosis Kit (Red, Elab Fluor® 555) is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures One-step TUNEL In Situ Apoptosis Kit (Red, Elab Fluor® 555)?

One-step TUNEL In Situ Apoptosis Kit (Red, Elab Fluor® 555) is manufactured by Elabscience.

What is the estimated delivery time for One-step TUNEL In Situ Apoptosis Kit (Red, Elab Fluor® 555)?

Estimated delivery time for One-step TUNEL In Situ Apoptosis Kit (Red, Elab Fluor® 555) is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for One-step TUNEL In Situ Apoptosis Kit (Red, Elab Fluor® 555)?

The safety data sheet for One-step TUNEL In Situ Apoptosis Kit (Red, Elab Fluor® 555) is available here: https://789.bio/eb/n5eTGS.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

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