TUNEL In Situ Apoptosis Kit (HRP-DAB Method)

Catalog number E-CK-A331-01

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Price for E-CK-A331-01

Size / count 20 Assays

Specifications

Catalog number: E-CK-A331-01
Size / count: 20 Assays
Dry ice: No
Hazardous: No
Discontinued: No
Detection Method: Colorimetric method
Assay Principle: When cells undergo apoptosis, endonuclease enzymes are activated to cleave the genomic DNA between nucleosomes. When genomic DNA is cleaved, the exposed 3'-OH can be added with a biotinylated dUTP (Biotin-dUTP) due to the catalysis of Terminal Deoxynucleotidyl Transferase (TdT), followed by the binding of horseradish Peroxidase-labeled Streptavidin (Streptavidin-HRP) . Thereafter, through the HRP catalysis, the apoptotic cells are marked by DAB, which can be detected by ordinary microscopy. This is the principle of TUNEL (TdT-mediated dUTP Nick-End Labeling) for detecting apoptosis.
Sample Type: Paraffin section; frozen section; cell slide
Shipping Conditions: Ice bag
Storage Conditions: This product can be stored at -20°C for 12 months with shading light.
Citation 01: https://link.springer.com/article/10.1186/s12943-024-02074-z
Citation 02: https://www.sciencedirect.com/science/article/pii/S2452199X25001860
Citation 03: https://advanced.onlinelibrary.wiley.com/doi/abs/10.1002/adfm.202420344
Citation 04: https://www.sciencedirect.com/science/article/pii/S2452199X25001781
Citation 05: https://pubs.acs.org/doi/abs/10.1021/acsnano.4c07085
Citation 06: https://onlinelibrary.wiley.com/doi/abs/10.1002/advs.202407493
Citation 07: https://onlinelibrary.wiley.com/doi/abs/10.1002/advs.202401731
Citation 08: https://advanced.onlinelibrary.wiley.com/doi/abs/10.1002/advs.202414468
Citation 09: https://www.sciencedirect.com/science/article/pii/S1385894724061448
Citation 10: https://www.sciencedirect.com/science/article/pii/S2213231724001058
Citation 11: https://aacrjournals.org/cancerres/article/doi/10.1158/0008-5472.CAN-23-1796/733406
Citation 12: https://www.sciencedirect.com/science/article/pii/S2213231723001842
Detection Instrument: Light microscope

Frequently Asked Questions

What is the catalog number for TUNEL In Situ Apoptosis Kit (HRP-DAB Method)?

The catalog number for TUNEL In Situ Apoptosis Kit (HRP-DAB Method) is E-CK-A331.

What sizes are available for TUNEL In Situ Apoptosis Kit (HRP-DAB Method)?

TUNEL In Situ Apoptosis Kit (HRP-DAB Method) is available in the following size(s): 20 Assays, 50 Assays, 100 Assays.

How many pack sizes does TUNEL In Situ Apoptosis Kit (HRP-DAB Method) come in?

TUNEL In Situ Apoptosis Kit (HRP-DAB Method) is available in 3 different pack sizes.

Is TUNEL In Situ Apoptosis Kit (HRP-DAB Method) in stock?

TUNEL In Situ Apoptosis Kit (HRP-DAB Method) is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures TUNEL In Situ Apoptosis Kit (HRP-DAB Method)?

TUNEL In Situ Apoptosis Kit (HRP-DAB Method) is manufactured by Elabscience.

What is the estimated delivery time for TUNEL In Situ Apoptosis Kit (HRP-DAB Method)?

Estimated delivery time for TUNEL In Situ Apoptosis Kit (HRP-DAB Method) is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for TUNEL In Situ Apoptosis Kit (HRP-DAB Method)?

The safety data sheet for TUNEL In Situ Apoptosis Kit (HRP-DAB Method) is available here: https://789.bio/eb/Xvbr90.

Do you offer custom or private-label production of this type of product?

Yes, custom antibody development and private-label production services are available. Contact our sales team to discuss your target, timeline, and quantity requirements.

What is the immunogen used to generate this antibody?

Immunogen or antigen details used to raise this antibody are listed on the product datasheet under immunogen information.

What is the recommended positive control for this assay?

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.