Caspase 1 Activity Assay Kit (Colorimetric Method)

Catalog number E-CK-A381-01

Choose a variant (2 options)

Selecting a variant updates its price, size and availability.

Price for E-CK-A381-01

Size / count 20 Assays

Specifications

Catalog number: E-CK-A381-01
Size / count: 20 Assays
Dry ice: No
Hazardous: No
Discontinued: No
Detection Method: Colorimetric method
Assay Principle: Caspase 1, also known as Interkeukin 1β Conberting Enzyme (ICE), is the only caspase in the caspase family that can cleave IL-1β prefixes or IL-18 prefabrication. Caspase 11 can cleave 45 kD caspase 1 preparation to produce 20 kD and 10 kD fragments, which can form heterodimer and further form tetramer by two heterodimers. Caspase 1 regulates apoptosis by cleaving Bcl-XL and the associated immune response by cleaving cytokine precursors, or regulates pyroptosis by hydrolyzing Gastermin D (GSDMD) . This caspase 1 activity assay kit is based on caspase 1 that can catalyze the substrate AC-YVAD-pNA to generate yellow pNA (p-Nitroaniline) . The pNA has a strong absorption near 405 nm, The activity of caspase 1 can be calculated by determining the absorbance at 405 nm.
Sample Type: Cell and tissue samples
Shipping Conditions: Ice bag
Storage Conditions: This product can be stored at -20°C for 12 months with shading light.
Citation 01: https://www.sciencedirect.com/science/article/pii/S0925521424005106
Citation 02: https://www.sciencedirect.com/science/article/pii/S0024320524005563
Citation 03: https://www.sciencedirect.com/science/article/pii/S1567576924022380
Citation 04: https://www.sciencedirect.com/science/article/pii/S0378874124016118
Citation 05: https://www.sciencedirect.com/science/article/pii/S1567576925007416
Citation 06: https://www.nature.com/articles/s41598-024-84959-z
Citation 07: https://www.sciencedirect.com/science/article/pii/S1043466625000225
Citation 08: https://www.ingentaconnect.com/content/ben/acamc/2023/00000023/00000001/art00012
Citation 09: https://www.frontiersin.org/articles/10.3389/frph.2023.1204728/full
Citation 10: https://www.sciencedirect.com/science/article/pii/S0928468017301451
Detection Instrument: Spectrophotometer; Microplate reader

Frequently Asked Questions

What is the catalog number for Caspase 1 Activity Assay Kit (Colorimetric Method)?

The catalog number for Caspase 1 Activity Assay Kit (Colorimetric Method) is E-CK-A381.

What sizes are available for Caspase 1 Activity Assay Kit (Colorimetric Method)?

Caspase 1 Activity Assay Kit (Colorimetric Method) is available in the following size(s): 20 Assays, 100 Assays.

How many pack sizes does Caspase 1 Activity Assay Kit (Colorimetric Method) come in?

Caspase 1 Activity Assay Kit (Colorimetric Method) is available in 2 different pack sizes.

Is Caspase 1 Activity Assay Kit (Colorimetric Method) in stock?

Caspase 1 Activity Assay Kit (Colorimetric Method) is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Caspase 1 Activity Assay Kit (Colorimetric Method)?

Caspase 1 Activity Assay Kit (Colorimetric Method) is manufactured by Elabscience.

What is the estimated delivery time for Caspase 1 Activity Assay Kit (Colorimetric Method)?

Estimated delivery time for Caspase 1 Activity Assay Kit (Colorimetric Method) is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Caspase 1 Activity Assay Kit (Colorimetric Method)?

The safety data sheet for Caspase 1 Activity Assay Kit (Colorimetric Method) is available here: https://789.bio/eb/XLef90.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.