Caspase 8 Activity Assay Kit (Colorimetric Method)

Catalog number E-CK-A388-01

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Price for E-CK-A388-01

Size / count 20 Assays

Specifications

Catalog number: E-CK-A388-01
Size / count: 20 Assays
Dry ice: No
Hazardous: No
Discontinued: No
Detection Method: Colorimetric method
Assay Principle: Caspase 8, also known as FLICE, MACH and Mch5 is self-activated or activated in response to granzyme B cleavage. Caspase 8 specifically recognizes IETD. Activated caspase 8 can not only cleave PARP, but also participate in the activation of other ICE family proteases, such as caspase 3 and caspase 7. This caspase 8 activity assay kit is based on caspase 8 that can catalyze the substrate Ac-IETD-pNA to generate yellow pNA (p-Nitroaniline) . The pNA has a strong absorption near 405 nm, The activity of caspase 8 can be calculated by determining the absorbance at 405 nm.
Sample Type: Cell and tissue samples
Shipping Conditions: Ice bag
Storage Conditions: This product can be stored at -20°C for 12 months with shading light.
Citation 01: https://www.sciencedirect.com/science/article/pii/S0141813025014394
Citation 02: https://www.frontiersin.org/articles/10.3389/fimmu.2021.748758/full
Citation 03: https://www.sciencedirect.com/science/article/pii/S0925521423001369
Citation 04: https://www.sciencedirect.com/science/article/pii/S0925521423003162
Citation 05: https://www.sciencedirect.com/science/article/pii/S0925521422002678
Citation 06: https://www.sciencedirect.com/science/article/pii/S0925521424005106
Citation 07: https://pmc.ncbi.nlm.nih.gov/articles/PMC11989111/
Citation 08: https://link.springer.com/article/10.1007/s12035-025-04810-y
Detection Instrument: Spectrophotometer; Microplate reader

Frequently Asked Questions

What is the catalog number for Caspase 8 Activity Assay Kit (Colorimetric Method)?

The catalog number for Caspase 8 Activity Assay Kit (Colorimetric Method) is E-CK-A388.

What sizes are available for Caspase 8 Activity Assay Kit (Colorimetric Method)?

Caspase 8 Activity Assay Kit (Colorimetric Method) is available in the following size(s): 20 Assays, 100 Assays.

How many pack sizes does Caspase 8 Activity Assay Kit (Colorimetric Method) come in?

Caspase 8 Activity Assay Kit (Colorimetric Method) is available in 2 different pack sizes.

Is Caspase 8 Activity Assay Kit (Colorimetric Method) in stock?

Caspase 8 Activity Assay Kit (Colorimetric Method) is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Caspase 8 Activity Assay Kit (Colorimetric Method)?

Caspase 8 Activity Assay Kit (Colorimetric Method) is manufactured by Elabscience.

What is the estimated delivery time for Caspase 8 Activity Assay Kit (Colorimetric Method)?

Estimated delivery time for Caspase 8 Activity Assay Kit (Colorimetric Method) is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Caspase 8 Activity Assay Kit (Colorimetric Method)?

The safety data sheet for Caspase 8 Activity Assay Kit (Colorimetric Method) is available here: https://789.bio/eb/SOy5G0.

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.

Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.