GWL Recombinant Rabbit Monoclonal Antibody [PSH07-69]

Catalog number HA722884

Price for HA722884

Size / count 100 µL

About this product

Serine/threonine kinase that plays a key role in M phase by acting as a regulator of mitosis entry and maintenance. Acts by promoting the inactivation of protein phosphatase 2A (PP2A) during M phase: does not directly inhibit PP2A but acts by mediating phosphorylation and subsequent activation of ARPP19 and ENSA at 'Ser-62' and 'Ser-67', respectively. ARPP19 and ENSA are phosphatase inhibitors that specifically inhibit the PPP2R2D (PR55-delta) subunit of PP2A. Inactivation of PP2A during M phase is essential to keep cyclin-B1-CDK1 activity high. Following DNA damage, it is also involved in checkpoint recovery by being inhibited. Phosphorylates histone protein in vitro; however such activity is unsure in vivo. May be involved in megakaryocyte differentiation.

Specifications

Catalog number: HA722884
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: 2700091H24Rik C88295 FLJ14813 GREATWALL Greatwall protein kinase GW GWL GWL_HUMAN hGWL MAST-L Mastl MGC117975 Microtubule associated serine/threonine kinase like Microtubule-associated serine/threonine-protein kinase-like RP11 85G18.2 Serine/threonine-protein kinase greatwall THC2
Abbreviation: GW; GWL; hGWL
Swiss Prot: Q96GX5 Human
Cellular Locus: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, Nucleus, Cleavage furrow.
Host: Rabbit
Species Reactivity: Human, Monkey
Immunogen: Recombinant protein within human GWL aa 1-350.
Isotype: IgG
Clone: PSH07-69
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IF-Cell, IP
Positive Control: HeLa cell lysate, LNCaP cell lysate, HepG2 cell lysate, MDA-MB-231 cell lysate, COS-1 cell lysate, HeLa.
Concentration: 1mg/mL
Dilution: WB: 1:2,000 ;IF-Cell: 1:50 ;IP: 1-2μg/sample
Purity: Protein A affinity purified.
Form: Liquid
Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 97 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for GWL Recombinant Rabbit Monoclonal Antibody [PSH07-69]?

The catalog number for GWL Recombinant Rabbit Monoclonal Antibody [PSH07-69] is HA722884.

What sizes are available for GWL Recombinant Rabbit Monoclonal Antibody [PSH07-69]?

GWL Recombinant Rabbit Monoclonal Antibody [PSH07-69] is available in the following size(s): 100 µL.

Is GWL Recombinant Rabbit Monoclonal Antibody [PSH07-69] in stock?

GWL Recombinant Rabbit Monoclonal Antibody [PSH07-69] is currently made to order / not held in immediate stock. Contact us for lead time.

What is GWL Recombinant Rabbit Monoclonal Antibody [PSH07-69] used for?

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.