Dicer Rabbit Polyclonal Antibody

Catalog number HA500522

Price for HA500522

Size / count 100 µL

About this product

Dicer, also known as endoribonuclease Dicer or helicase with RNase motif, is an enzyme that in humans is encoded by the DICER1 gene. Being part of the RNase III family, Dicer cleaves double-stranded RNA (dsRNA) and pre-microRNA (pre-miRNA) into short double-stranded RNA fragments called small interfering RNA and microRNA, respectively. These fragments are approximately 20–25 base pairs long with a two-base overhang on the 3′-end. Dicer facilitates the activation of the RNA-induced silencing complex (RISC), which is essential for RNA interference. RISC has a catalytic component Argonaute, which is an endonuclease capable of degrading messenger RNA (mRNA).

Specifications

Catalog number: HA500522
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: DCR antibody DCR1 antibody Dicer 1 ribonuclease III antibody Dicer 1 ribonuclease type III antibody Dicer antibody DICER_HUMAN antibody DICER1 antibody Double-strand-specific ribonuclease antibody Endoribonuclease Dicer antibody Helicase MOI antibody Helicase with RNase motif antibody HERNA antibody KIAA0928 antibody MNG1 antibody RMSE2 antibody
Abbreviation: DICER1, DICER, HERNA, KIAA0928
Swiss Prot: Q9UPY3 Human, Q8R418 Mouse
Cellular Locus: Cytoplasm, perinuclear region.
Host: Rabbit
Species Reactivity: Human, Mouse
Immunogen: Recombinant protein within human aa 701-1,100 / 1,922.
Isotype: IgG
Conjugation: Non-conjugated
Type: Rabbit polyclonal Antibody
Applications: WB, IF-Cell, FC
Positive Control: MCF-7 cell lysate, 293 cell lysate, Daudi cell lysate, MCF-7, C2C12.
Concentration: 2 mg/mL
Dilution: WB: 1:1,000;IF-Cell: 10ug/mL;FC: 1ug/mL
Purity: Immunogen affinity purified.
Form: Liquid
Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 218 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for Dicer Rabbit Polyclonal Antibody?

The catalog number for Dicer Rabbit Polyclonal Antibody is HA500522.

What sizes are available for Dicer Rabbit Polyclonal Antibody?

Dicer Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is Dicer Rabbit Polyclonal Antibody in stock?

Dicer Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is Dicer Rabbit Polyclonal Antibody used for?

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.