DMAP1 Recombinant Rabbit Monoclonal Antibody [JE55-31]

About this product

DNA methyltransferase 1-associated protein 1 is an enzyme that in humans is encoded by the DMAP1 gene. This gene encodes a subunit of several, distinct complexes involved in the repression or activation of transcription. The encoded protein can independently repress transcription and is targeted to replication foci throughout S phase by interacting directly with the N-terminus of DNA methyltransferase 1. During late S phase, histone deacetylase 2 is added to this complex, providing a means to deacetylate histones in transcriptionally inactive heterochromatin following replication. The encoded protein is also a component of the nucleosome acetyltransferase of H4 complex and interacts with the transcriptional corepressor tumor susceptibility gene 101 and the pro-apoptotic death-associated protein 6, among others. Alternatively spliced transcript variants encoding the same protein have been described.

Specifications

Catalog number

HA722002

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

DKFZp686L09142 antibody DMAP 1 antibody DMAP1 antibody DMAP1_HUMAN antibody DNA methyltransferase 1 associated protein 1 antibody DNA methyltransferase 1-associated protein 1 antibody DNMAP 1 antibody DNMAP1 antibody DNMT1 associated protein 1 antibody DNMT1-associated protein 1 antibody DNMTAP 1 antibody DNMTAP1 antibody EAF 2 antibody EAF2 antibody FLJ11543 antibody KIAA1425 antibody MAT 1 mediated transcriptional repressor antibody MGC55593 antibody SWC 4 antibody SWC4 antibody zgc:55593 antibody

Abbreviation

DMAP1, KIAA1425

Swiss Prot

Q9NPF5 Human, Q9JI44 Mouse, Q568Y6 Rat

Cellular Locus

Nucleus, Cytoplasm.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein within Human DMAP1 aa 368-467 / 467.

Isotype

IgG

Clone

JE55-31

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, IHC-P, FC

Positive Control

HeLa cell lysate, HEK-293 cell lysate, HepG2 cell lysate, MCF7 cell lysate, Jurkat cell lysate, K-562 cell lysate, NIH/3T3 cell lysate, Neuro-2a cell lysate, F9 cell lysate, PC-12 cell lysate, HeLa, F9, human small intestine tissue, human testis tissue, mouse colon tissue, rat colon tissue.

Concentration

1 mg/mL

Dilution

WB: 1:1,000 ;IF-Cell: 1:100 ;IHC-P: 1:50 ;FC: 1:1,000

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 53 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes