Tripeptidyl peptidase II Recombinant Rabbit Monoclonal Antibody [JE75-27]

Catalog number HA722476

Price for HA722476

Size / count 100 µL

About this product

Cytosolic tripeptidyl-peptidase that releases N-terminal tripeptides from polypeptides and is a component of the proteolytic cascade acting downstream of the 26S proteasome in the ubiquitin-proteasome pathway. It plays an important role in intracellular amino acid homeostasis. The limitation of proteolytic products to tripeptides is achieved by tailoring the size of the substrate-binding cleft: the two negatively charged residues Glu-305 and Glu-331 that are blocking position P4 limit the number of residues that can be accommodated in the binding cleft and thus create a molecular ruler. At the same time, they orient substrates so that the tripeptides are removed exclusively from the N-terminus.

Specifications

Catalog number: HA722476
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: TPP II antibody TPP2 antibody Tripeptidyl aminopeptidase antibody Tripeptidyl peptidase 2 antibody Tripeptidyl peptidase II antibody
Abbreviation: Tripeptidyl-peptidase 2 TPP-2 Tripeptidyl aminopeptidase Tripeptidyl-peptidase II (TPP-II) TPP2
Swiss Prot: P29144 Human, Q64514 Mouse, Q64560 Rat
Cellular Locus: Cytoplasm, Nucleus.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Recombinant protein within Human Tripeptidyl peptidase II aa 881-1,180 / 1,249.
Isotype: IgG
Clone: JE75-27
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IHC-P, IF-Cell, FC
Positive Control: HeLa cell lysate, HEK-293 cell lysate, SW620 cell lysate, RPMI 8226 cell lysate, NIH/3T3 cell lysate, F9 cell lysate, C6 cell lysate, SW620, NIH/3T3, human colon cancer tissue, human testis tissue, human liver tissue, mouse liver tissue, rat liver tissue, C6.
Concentration: 1 mg/mL
Dilution: WB: 1:1,000 ;IHC-P: 1:1,000 ;IF-Cell: 1:50 ;FC: 1:500-1:1,000
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 138 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for Tripeptidyl peptidase II Recombinant Rabbit Monoclonal Antibody [JE75-27]?

The catalog number for Tripeptidyl peptidase II Recombinant Rabbit Monoclonal Antibody [JE75-27] is HA722476.

What sizes are available for Tripeptidyl peptidase II Recombinant Rabbit Monoclonal Antibody [JE75-27]?

Tripeptidyl peptidase II Recombinant Rabbit Monoclonal Antibody [JE75-27] is available in the following size(s): 100 µL.

Is Tripeptidyl peptidase II Recombinant Rabbit Monoclonal Antibody [JE75-27] in stock?

Tripeptidyl peptidase II Recombinant Rabbit Monoclonal Antibody [JE75-27] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Tripeptidyl peptidase II Recombinant Rabbit Monoclonal Antibody [JE75-27] used for?

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.

How do I reconstitute this lyophilized product?

Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.