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Product details

MYH2 Recombinant Rabbit Monoclonal Antibody [JE53-30]

Catalog number HA721862

Price for HA721862

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Size / count 100 µL

About this product

Defects in MYH2 are the cause of inclusion body myopathy type 3 (IBM3) [MIM:605637]. Hereditary inclusion body myopathies constitute a group of neuromuscular disorders characterized by slowly progressive distal and proximal weakness and a typical muscle pathology including rimmed vacuoles and filamentous inclusions. IBM3 is a variant of hereditary inclusion body myopathies and is characterized by autosomal dominant myopathy with joint contracture, ophthalmoplegia and rimmed vacuoles. Morphological analysis of muscle biopsies from patients indicate that the type 2A fibers frequently were abnormal, whereas other fiber types appeared normal.

Specifications

Catalog number
HA721862
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
adult 2 antibody Fast 2a myosin heavy chain antibody IBM3 antibody Inclusion body myopathy 3, autosomal dominant antibody MYH2 antibody MYH2_HUMAN antibody MYH2A antibody MYHas8 antibody MyHC IIa antibody MyHC-2a antibody MyHC-IIa antibody MYHSA2 antibody Myosin heavy chain 2 antibody Myosin heavy chain 2a antibody Myosin heavy chain antibody Myosin heavy chain IIa antibody Myosin heavy chain skeletal muscle adult 2 antibody Myosin heavy polypeptide 2 skeletal muscle adult antibody Myosin-2 antibody MYPOP antibody skeletal muscle antibody Type IIA myosin heavy chain antibody
Abbreviation
Myosin-2 Myosin heavy chain 2 Myosin heavy chain 2a (MyHC-2a) Myosin heavy chain IIa (MyHC-IIa) Myosin heavy chain, skeletal muscle, adult 2 MYH2 MYHSA2
Swiss Prot
Q9UKX2 Human, Q5SX41 Mouse, Q07443 Rat
Cellular Locus
Cytoplasm.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein within Human MYH2 aa 30-129 / 1,941.
Isotype
IgG
Clone
JE53-30
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P
Positive Control
Mouse skeletal muscle tissue lysate, rat skeletal muscle tissue lysate, human skeletal muscle tissue, mouse skeletal muscle tissue, rat skeletal muscle tissue.
Concentration
1 mg/mL
Dilution
WB: 1:1,000 ;IHC-P: 1:5,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 223 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for MYH2 Recombinant Rabbit Monoclonal Antibody [JE53-30]?

The catalog number for MYH2 Recombinant Rabbit Monoclonal Antibody [JE53-30] is HA721862.

What sizes are available for MYH2 Recombinant Rabbit Monoclonal Antibody [JE53-30]?

MYH2 Recombinant Rabbit Monoclonal Antibody [JE53-30] is available in the following size(s): 100 µL.

Is MYH2 Recombinant Rabbit Monoclonal Antibody [JE53-30] in stock?

MYH2 Recombinant Rabbit Monoclonal Antibody [JE53-30] is currently made to order / not held in immediate stock. Contact us for lead time.

What is MYH2 Recombinant Rabbit Monoclonal Antibody [JE53-30] used for?

Defects in MYH2 are the cause of inclusion body myopathy type 3 (IBM3) [MIM:605637]. Hereditary inclusion body myopathies constitute a group of neuromuscular disorders characterized by slowly progressive distal and proximal weakness and a typical muscle pathology including rimmed vacuoles and filame

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.

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