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Product details

Insulin (E2-E3), CF740 conjugate, 0.1mg/mL

Catalog number BNC740281-100

Price for BNC740281-100

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Size / count 1x 100 µL

About this product

Recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-terminal basic residue. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids. Deficiency of insulin results in diabetes mellitus. The main storage site for insulin is the pancreatic islets. Antibodies to insulin are important as beta-cell and insulinoma marker.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC740281-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
IDDM2, ILPR, IRDN, MODY10, Proinsulin
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
INS
Gene ID
3630
NCBI Gene ID
272259
UniProt
P01308
Swiss Prot
P01308
Host
Mouse
Species Reactivity
Cow, Human, Mouse, Pig, Rabbit
Reactivity
Insulin
Immunogen
Purified pig insulin, conjugated to KLH
Target Antigen
Insulin
Clonality
Monoclonal
Clone
E2-E3
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, frozen (published) |IHC, FFPE (verified)
Field of Research
Endocrinology
Positive Control
MIA PaCa-2 cells or Pancreas
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% rBSA, 0.05% azide
Molecular Weight
6 kDa
References & Citations
Note: References for this clone sold by other suppliers may be listed for expected applications. Metabolism Clinical Experimental (2007) 56: 142-151. (IHC, frozen)
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), Bos taurus (bovine)
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF740

Frequently Asked Questions

What is the catalog number for Insulin (E2-E3), CF740 conjugate, 0.1mg/mL?

The catalog number for Insulin (E2-E3), CF740 conjugate, 0.1mg/mL is BNC740281-100.

What sizes are available for Insulin (E2-E3), CF740 conjugate, 0.1mg/mL?

Insulin (E2-E3), CF740 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Insulin (E2-E3), CF740 conjugate, 0.1mg/mL in stock?

Insulin (E2-E3), CF740 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Insulin (E2-E3), CF740 conjugate, 0.1mg/mL?

Insulin (E2-E3), CF740 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Insulin (E2-E3), CF740 conjugate, 0.1mg/mL?

Estimated delivery time for Insulin (E2-E3), CF740 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Insulin (E2-E3), CF740 conjugate, 0.1mg/mL?

The safety data sheet for Insulin (E2-E3), CF740 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02a3061270361e105000/msds/bnc740281-100.pdf.

What is Insulin (E2-E3), CF740 conjugate, 0.1mg/mL used for?

Recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-terminal basic

How do I reconstitute this lyophilized product?

Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

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