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Product details
Catalog number BNC742208-100
Price for BNC742208-100
Size / count 1x 100 µL
This antibody recognizes a protein of 120-80 kDa, identified as E-cadherin. Cadherins comprise a family of calcium-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. The classical cadherins, E-, N- and P-cadherin, consist of large extracellular domains characterized by a series of five homologous NH2 terminal repeats. The relatively short intracellular domains interact with a variety of cytoplasmic proteins, such as beta-catenin, to regulate cadherin function. E-cadherin plays an important role in epithelial cell adhesion. A decreased expression of E-cadherin is associated with metastatic potential and poor prognosis in breast cancer, prostate and esophageal cancer. In combination with p120 Catenin, it is useful for the differentiation between ductal (E-cadherin) and lobular (E-cadherin -) breast carcinomas. It may also help in diagnosis of mesothelioma.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for E-Cadherin (CDH1) / CD324 (Intercellular Junction Marker) (CDH1/2208R), CF740 conjugate, 0.1mg/mL is BNC742208-100.
E-Cadherin (CDH1) / CD324 (Intercellular Junction Marker) (CDH1/2208R), CF740 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.
E-Cadherin (CDH1) / CD324 (Intercellular Junction Marker) (CDH1/2208R), CF740 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
E-Cadherin (CDH1) / CD324 (Intercellular Junction Marker) (CDH1/2208R), CF740 conjugate, 0.1mg/mL is manufactured by Biotium.
Estimated delivery time for E-Cadherin (CDH1) / CD324 (Intercellular Junction Marker) (CDH1/2208R), CF740 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for E-Cadherin (CDH1) / CD324 (Intercellular Junction Marker) (CDH1/2208R), CF740 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02aa061270361e10776a/msds/bnc742208-100.pdf.
This antibody recognizes a protein of 120-80 kDa, identified as E-cadherin. Cadherins comprise a family of calcium-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. The classical cadherins, E-, N- and P-cadherin
We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.
Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.
Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.
