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Product details

Luteinizing Hormone beta (LH beta) (LHb/1214), CF740 conjugate, 0.1mg/mL

Catalog number BNC741214-500

Price for BNC741214-500

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Size / count 1x 500 µL

About this product

Luteinizing hormone (LH) is a glycoprotein. Each monomeric unit is a sugar-like protein molecule; two of these make the full, functional protein. Its structure is similar to the other glycoproteins, follicle-stimulating hormone (FSH), thyroid-stimulating hormone (TSH), and human chorionic gonadotropin (hCG) . The protein dimer contains 2 polypeptide units, labeled alpha and beta subunits that are connected by two bridges. The alpha subunits of LH, FSH, TSH, and hCG are identical, and contain 92 amino acids. The beta subunits vary. LH has a beta subunit of 121 amino acids (LHB) that confers its specific biologic action and is responsible for interaction with the LH receptor. This beta subunit contains the same amino acids in sequence as the beta subunit of hCG and both stimulate the same receptor; however, the hCG beta subunit contains an additional 24 amino acids and the hormones differ in the composition of their sugar moieties.LH is synthesized and secreted by gonadotrophs in the anterior lobe of the pituitary gland. In concert with the other pituitary gonadotropin follicle-stimulating hormone (FSH), it is necessary for proper reproductive function. In the female, an acute rise of LH levels triggers ovulation. In the male, where LH has also been called Interstitial Cell-Stimulating Hormone (ICSH), it stimulates Leydig cell production of testosterone. LH is a useful marker in classification of pituitary tumors and the study of pituitary disease.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC741214-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Chorionic Gonadotropin, Beta polypeptide 4 (CGB4) ; hLHB; Interstitial cell stimulating hormone beta chain; Leutropin; LH-B; LHB; LSH-B; LSH-beta; Luteinizing hormone beta polypeptide; Lutropin beta chain
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
LHB
Gene ID
3972
NCBI Gene ID
154704
UniProt
P01229
Swiss Prot
P01229
Host
Mouse
Species Reactivity
Human
Reactivity
Luteinizing Hormone-Beta
Immunogen
Recombinant beta sub-unit of human LH
Target Antigen
Luteinizing Hormone-Beta
Clonality
Monoclonal
Clone
LHb/1214
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Field of Research
Cancer, Endocrinology
Positive Control
Anterior Pituitary
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% rBSA, 0.05% azide
Molecular Weight
22 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), Bos taurus (bovine)
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF740

Frequently Asked Questions

What is the catalog number for Luteinizing Hormone beta (LH beta) (LHb/1214), CF740 conjugate, 0.1mg/mL?

The catalog number for Luteinizing Hormone beta (LH beta) (LHb/1214), CF740 conjugate, 0.1mg/mL is BNC741214-500.

What sizes are available for Luteinizing Hormone beta (LH beta) (LHb/1214), CF740 conjugate, 0.1mg/mL?

Luteinizing Hormone beta (LH beta) (LHb/1214), CF740 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Luteinizing Hormone beta (LH beta) (LHb/1214), CF740 conjugate, 0.1mg/mL in stock?

Luteinizing Hormone beta (LH beta) (LHb/1214), CF740 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Luteinizing Hormone beta (LH beta) (LHb/1214), CF740 conjugate, 0.1mg/mL?

Luteinizing Hormone beta (LH beta) (LHb/1214), CF740 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Luteinizing Hormone beta (LH beta) (LHb/1214), CF740 conjugate, 0.1mg/mL?

Estimated delivery time for Luteinizing Hormone beta (LH beta) (LHb/1214), CF740 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Luteinizing Hormone beta (LH beta) (LHb/1214), CF740 conjugate, 0.1mg/mL?

The safety data sheet for Luteinizing Hormone beta (LH beta) (LHb/1214), CF740 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02b9061270361e10c4eb/msds/bnc741214-500.pdf.

What is Luteinizing Hormone beta (LH beta) (LHb/1214), CF740 conjugate, 0.1mg/mL used for?

Luteinizing hormone (LH) is a glycoprotein. Each monomeric unit is a sugar-like protein molecule; two of these make the full, functional protein. Its structure is similar to the other glycoproteins, follicle-stimulating hormone (FSH), thyroid-stimulating hormone (TSH), and human chorionic gonadotrop

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.

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