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Product details

Rb1 (Tumor Suppressor Protein) (RB1/2313R), CF740 conjugate, 0.1mg/mL

Catalog number BNC742313-100

Price for BNC742313-100

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Size / count 1x 100 µL

About this product

This antibody recognizes a 105 kDa phosphoprotein, identified as retinoblastoma (Rb) gene product. Its epitope is localized between aa 703-772. It shows no cross reaction with p107 or p130. It specifically stains the nuclei of BT-20 cells and primary human foreskin fibroblast (HFF) cells. It does not stain the Rb-negative BT549 cells. It reacts with the hyperphosphorylated as well as the un (under) phosphorylated form of the Rb protein. Retinoblastoma gene product plays a key role in cell cycle control. It has been identified as a tumor suppressor gene whose loss of its function leads to tumor development. It is widely expressed in a variety of human tissues including breast, esophageal, squamous cell and cervical carcinoma.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC742313-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
OSRC; Osteosarcoma; p105-Rb; PP105; pp110; pRb; Prepro retinoblastoma associated protein; RB1; Retinoblastoma 1; Retinoblastoma-associated protein
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
RB1
Gene ID
5925
NCBI Gene ID
408528
UniProt
P06400
Swiss Prot
P06400
Host
Rabbit
Species Reactivity
Human, Mouse
Reactivity
Rb1
Immunogen
Recombinant full-length human Rb1 protein
Target Antigen
Rb1
Clonality
Recombinant Monoclonal
Clone
RB1/2313R
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Field of Research
Tumor suppressors
Positive Control
HeLa, A431 or BT-20 cells. Breast or Colon carcinoma.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% rBSA, 0.05% azide
Molecular Weight
105 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG
Species
Oryctolagus cuniculus (domestic rabbit), Bos taurus (bovine)
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF740

Frequently Asked Questions

What is the catalog number for Rb1 (Tumor Suppressor Protein) (RB1/2313R), CF740 conjugate, 0.1mg/mL?

The catalog number for Rb1 (Tumor Suppressor Protein) (RB1/2313R), CF740 conjugate, 0.1mg/mL is BNC742313-100.

What sizes are available for Rb1 (Tumor Suppressor Protein) (RB1/2313R), CF740 conjugate, 0.1mg/mL?

Rb1 (Tumor Suppressor Protein) (RB1/2313R), CF740 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Rb1 (Tumor Suppressor Protein) (RB1/2313R), CF740 conjugate, 0.1mg/mL in stock?

Rb1 (Tumor Suppressor Protein) (RB1/2313R), CF740 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Rb1 (Tumor Suppressor Protein) (RB1/2313R), CF740 conjugate, 0.1mg/mL?

Rb1 (Tumor Suppressor Protein) (RB1/2313R), CF740 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Rb1 (Tumor Suppressor Protein) (RB1/2313R), CF740 conjugate, 0.1mg/mL?

Estimated delivery time for Rb1 (Tumor Suppressor Protein) (RB1/2313R), CF740 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Rb1 (Tumor Suppressor Protein) (RB1/2313R), CF740 conjugate, 0.1mg/mL?

The safety data sheet for Rb1 (Tumor Suppressor Protein) (RB1/2313R), CF740 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0298061270361e100bcc/msds/bnc742313-100.pdf.

What is Rb1 (Tumor Suppressor Protein) (RB1/2313R), CF740 conjugate, 0.1mg/mL used for?

This antibody recognizes a 105 kDa phosphoprotein, identified as retinoblastoma (Rb) gene product. Its epitope is localized between aa 703-772. It shows no cross reaction with p107 or p130. It specifically stains the nuclei of BT-20 cells and primary human foreskin fibroblast (HFF) cells. It does no

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

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