SREBP2 (SREBP2/1579), CF740 conjugate, 0.1mg/mL

Catalog number BNC741579-500

Price for BNC741579-500

Size / count 1x 500 µL

About this product

The low density lipoprotein (LDL) receptor mediates the endocytic uptake of cholesterol-carrying lipoproteins, thereby controlling cholesterol levels in cells and plasma. Transcription of the LDL receptor gene is controlled by a ten base pair sequence in the 5' flanking region, designated sterol regulatory element 1 (SRE-1) . When cellular sterol stores are depleted, the element is activated, the gene is transcribed and the cellular uptake of LDL increases. A set of SREbinding proteins (SREBPs) have been identified, including two basic helixloop-helix-leucine zipper (bHLH-zip) transcription factors, designated SREBP-1 and SREBP-2. SREBP-1 and SREBP-2 have been shown to have the same specificity for SRE-1 in vitro and to activate the transcription of reporter genes containing SRE-1 in the same way. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC741579-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: AI608257; bHLHd2; Class D basic helix-loop-helix protein 2; OTTHUMP00000028740; Processed sterol regulatory element-binding protein 2; SRBP2_HUMAN; SREBF 2; Srebf2; SREBF2 protein; SREBP 2; SREBP2; SREBP2gc; sterol regulatory element binding factor 2; Sterol regulatory element binding transcription factor 2
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: SREBF2
Gene ID: 6721
NCBI Gene ID: 443258
UniProt: Q12772
Swiss Prot: Q12772
Host: Mouse
Species Reactivity: Human
Reactivity: SREBP2
Immunogen: Recombinant full-length human SREBF2 protein
Target Antigen: SREBP2
Clonality: Monoclonal
Clone: SREBP2/1579
Type: Primary
Source: Animal
Origin: Animal
Positive Control: Ubiqutious expression in adult and fetal tissues. Hep2 or HeLa cells.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% rBSA, 0.05% azide
Molecular Weight: 68/125 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), Bos taurus (bovine)
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF740

Frequently Asked Questions

What is the catalog number for SREBP2 (SREBP2/1579), CF740 conjugate, 0.1mg/mL?

The catalog number for SREBP2 (SREBP2/1579), CF740 conjugate, 0.1mg/mL is BNC741579-500.

What sizes are available for SREBP2 (SREBP2/1579), CF740 conjugate, 0.1mg/mL?

SREBP2 (SREBP2/1579), CF740 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is SREBP2 (SREBP2/1579), CF740 conjugate, 0.1mg/mL in stock?

SREBP2 (SREBP2/1579), CF740 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures SREBP2 (SREBP2/1579), CF740 conjugate, 0.1mg/mL?

SREBP2 (SREBP2/1579), CF740 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for SREBP2 (SREBP2/1579), CF740 conjugate, 0.1mg/mL?

Estimated delivery time for SREBP2 (SREBP2/1579), CF740 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for SREBP2 (SREBP2/1579), CF740 conjugate, 0.1mg/mL?

The safety data sheet for SREBP2 (SREBP2/1579), CF740 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029c061270361e10222c/msds/bnc741579-500.pdf.

What is SREBP2 (SREBP2/1579), CF740 conjugate, 0.1mg/mL used for?

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.