ERCC1 / RAD10 (Tumor Progression Marker) (ERCC1/2318), CF740 conjugate, 0.1mg/mL

Catalog number BNC742318-500

Price for BNC742318-500

Size / count 1x 500 µL

About this product

Recognizes a protein of 110 kDa, identified as Excision Repair Cross Complementing 1 (ERCC1) . It is a mammalian nucleotide excision repair (NER) enzyme involved in repair of damaged DNA. ERCC1 is a homologous to RAD10 in Saccharomyces cerevisiae, which is required in mitotic intrachromosomal recombination and repair. ERCC1 is required in repair of cisplatin-induced DNA adducts and ultraviolet (UV) -induced DNA damage. High expression of ERCC1 has been linked to tumor progression in a variety of cancers including non-small cell lung cancer (NSCLC), squamous cell carcinoma of the head, ovarian cancer and esophageal cancer. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC742318-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: COFS4; DNA excision repair protein ERCC1; ERCC1; Excision repair cross complementing 1; RAD10; UV20
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: ERCC1
Gene ID: 2067
NCBI Gene ID: 435981
UniProt: P07992
Swiss Prot: P07992
Host: Mouse
Species Reactivity: Human
Reactivity: ERCC1|RAD10
Immunogen: Recombinant fragment (around aa 191-281) of human ERCC1 protein (exact sequence is proprietary)
Target Antigen: ERCC1 | RAD10
Clonality: Monoclonal
Clone: ERCC1/2318
Type: Primary
Source: Animal
Origin: Animal
Positive Control: HeLa, HepG2 cells. Tonsil or Prostate.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% rBSA, 0.05% azide
Molecular Weight: ~110 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2b, kappa
Species: Mus musculus (mouse), Bos taurus (bovine)
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF740

Frequently Asked Questions

What is the catalog number for ERCC1 / RAD10 (Tumor Progression Marker) (ERCC1/2318), CF740 conjugate, 0.1mg/mL?

The catalog number for ERCC1 / RAD10 (Tumor Progression Marker) (ERCC1/2318), CF740 conjugate, 0.1mg/mL is BNC742318-500.

What sizes are available for ERCC1 / RAD10 (Tumor Progression Marker) (ERCC1/2318), CF740 conjugate, 0.1mg/mL?

ERCC1 / RAD10 (Tumor Progression Marker) (ERCC1/2318), CF740 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is ERCC1 / RAD10 (Tumor Progression Marker) (ERCC1/2318), CF740 conjugate, 0.1mg/mL in stock?

ERCC1 / RAD10 (Tumor Progression Marker) (ERCC1/2318), CF740 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures ERCC1 / RAD10 (Tumor Progression Marker) (ERCC1/2318), CF740 conjugate, 0.1mg/mL?

ERCC1 / RAD10 (Tumor Progression Marker) (ERCC1/2318), CF740 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for ERCC1 / RAD10 (Tumor Progression Marker) (ERCC1/2318), CF740 conjugate, 0.1mg/mL?

Estimated delivery time for ERCC1 / RAD10 (Tumor Progression Marker) (ERCC1/2318), CF740 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for ERCC1 / RAD10 (Tumor Progression Marker) (ERCC1/2318), CF740 conjugate, 0.1mg/mL?

The safety data sheet for ERCC1 / RAD10 (Tumor Progression Marker) (ERCC1/2318), CF740 conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is ERCC1 / RAD10 (Tumor Progression Marker) (ERCC1/2318), CF740 conjugate, 0.1mg/mL used for?

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.