Interferon gamma (IFNG) (G-23), CF647 conjugate, 0.1mg/mL

About this product

This antibody recognizes a protein of 20-25 kDa, identified as human interferon gamma (IFN-γ ) . Multiple forms exist due to variable glycosylation and under non-denaturing conditions due to dimers and tetramers. T lymphocytes and NK cells mainly produce IFN-γ . It is a pleiotropic cytokine involved in the regulation of nearly all phases of immune and inflammatory responses, including the activation, growth and differentiation of T cell, B cells, macrophages, NK cells and other cell types such as endothelial cells and fibroblasts. It has weak anti-viral and anti-proliferative activity, and potentiates the antiviral and anti-tumor effects of IFN-γ (type I interferon) .Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number

BNC470219-500

Size / count

1x 500 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9007-83-4

Synonyms

AMCF1; Beta thromboglobulin like protein; CXC chemokine ligand 8 (CXCL8) ; Emoctakin; Granulocyte chemotactic protein 1 (GCP1) ; IFG; IFI; IFN Immune; IFN-gamma (IFNG) ; Interleukin 8; Interferon gamma; LECT; LUCT; Lymphocyte derived neutrophil activating factor; LYNAP; Macrophage Activating Factor (MAF) ; Monocyte derived neutrophil activating protein (MONAP) ; Monocyte derived neutrophil chemotactic factor (MDNCF) ; Neutrophil activating factor (NAF) ; Neutrophil activating peptide 1 (NAP1) ; Neutrophil activating protein 1 (NAP1) ; SCYB8; T cell chemotactic factor; T Cell Interferon; Type II Interferon

UNSPSC

41116161

UNSPSC Description

Primary and secondary antibodies for multiple methodology immunostaining detection application

Gene Name

IFNG

Gene ID

3458

NCBI Gene ID

856

UniProt

P01579

Swiss Prot

P01579

Host

Mouse

Species Reactivity

Human

Reactivity

Interferon Gamma

Immunogen

Purified recombinant human IFN-gamma

Target Antigen

Interferon Gamma

Clonality

Monoclonal

Clone

G-23

Type

Primary

Source

Animal

Origin

Animal

Applications

IHC, FFPE (published) |IHC, frozen (published)

Positive Control

PMA stimulated human peripheral blood mononuclear cells.

Stability

2 years

Concentration

0.1 mg/mL

Buffer

PBS, 0.1% BSA, 0.05% azide

Molecular Weight

20-25 kDa

References & Citations

Note: References for this clone sold by other suppliers may be listed for expected applications. Eur J Dermatol (2011) 21(1): 53-7. (IHC, frozen) Infection Immunity (2005) 73(7): 3923-3928. (IHC, FFPE)

Shipping Conditions

RT (ND)

Storage Conditions

Stable at room temperature or 37°C (98°F) for 7 days.

Notes

Protect from light

Shelf Life

Guaranteed for at least 24 months from date of receipt when stored as recommended

Fragment

IgG1, kappa

Species

Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.

Classification

0.05% sodium azide (CAS 26628-22-8)

Conjugate

CF647