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Product details

Cytokeratin, pan (Cocktail PAN-CK), CF740 conjugate, 0.1mg/mL

Catalog number BNC740999-100

Price for BNC740999-100

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Size / count 1x 100 µL

About this product

Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. This antibody cocktail recognizes acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins, with 67 kDa (CK1) ; 64 kDa (CK3) ; 59 kDa (CK4) ; 58 kDa (CK5) ; 56 kDa (CK6) ; 55 kDa (CK7) ; 52 kDa (CK8) ; 56.5 kDa (CK10) ; 53 kDa (CK13) ; 50 kDa (CK14) ; 50 kDa (CK15) ; 48 kDa (CK16) ; 46 kDa (CK17) ; 45 kDa (CK18) and 40 kDa (CK19) . Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. KRT-PAN is a broad spectrum anti pan-cytokeratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer. It is useful in characterizing the source of various neoplasms and to study the distribution of cytokeratin containing cells in epithelia during normal development and during the development of epithelial neoplasms. This antibody stains cytokeratins present in normal and abnormal human tissues and shows high sensitivity in the recognition of epithelial cells and carcinomas. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC740999-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
K1B; KRT1B; Keratin, type II cytoskeletal 1b; K77; CK-1B; Keratin 1B; Keratin-77; Cytokeratin-1B; Type-II Keratin Kb39
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
KRT76, KRT77
Gene ID
374454 (KRT77) & 51350 (KRT76)
NCBI Gene ID
334989 (KRT77); 654392 (KRT76)
UniProt
Q7Z794 (KRT77); Q01546 (KRT76)
Swiss Prot
Q7Z794 (KRT77) & Q01546 (KRT76)
Host
Mouse
Species Reactivity
Chicken, Cow, Dog, Human, Monkey, Mouse, Rabbit, Rat
Reactivity
Cytokeratin, pan
Immunogen
Human epidermal keratin
Target Antigen
Cytokeratin, pan
Clonality
Monoclonal
Clone
Cocktail PAN-CK
Type
Primary
Source
Animal
Origin
Animal
Applications
Flow, intracellular (verified) |IF (verified) |IHC, FFPE (verified)
Field of Research
Cancer, Cytoskeleton
Positive Control
Skin, Adeno- or Squamous carcinomas
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% rBSA, 0.05% azide
Molecular Weight
40-67 kDa (Multiple)
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG' s
Species
Mus musculus (mouse), Bos taurus (bovine)
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF740

Frequently Asked Questions

What is the catalog number for Cytokeratin, pan (Cocktail PAN-CK), CF740 conjugate, 0.1mg/mL?

The catalog number for Cytokeratin, pan (Cocktail PAN-CK), CF740 conjugate, 0.1mg/mL is BNC740999-100.

What sizes are available for Cytokeratin, pan (Cocktail PAN-CK), CF740 conjugate, 0.1mg/mL?

Cytokeratin, pan (Cocktail PAN-CK), CF740 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Cytokeratin, pan (Cocktail PAN-CK), CF740 conjugate, 0.1mg/mL in stock?

Cytokeratin, pan (Cocktail PAN-CK), CF740 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Cytokeratin, pan (Cocktail PAN-CK), CF740 conjugate, 0.1mg/mL?

Cytokeratin, pan (Cocktail PAN-CK), CF740 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Cytokeratin, pan (Cocktail PAN-CK), CF740 conjugate, 0.1mg/mL?

Estimated delivery time for Cytokeratin, pan (Cocktail PAN-CK), CF740 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Cytokeratin, pan (Cocktail PAN-CK), CF740 conjugate, 0.1mg/mL?

The safety data sheet for Cytokeratin, pan (Cocktail PAN-CK), CF740 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02a3061270361e104d0a/msds/bnc740999-100.pdf.

What is Cytokeratin, pan (Cocktail PAN-CK), CF740 conjugate, 0.1mg/mL used for?

Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. This antibody cocktail recognizes acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins, with 67 kDa (CK1) ; 64 kDa (CK3) ; 59 kDa (CK4) ; 58 kDa (CK5) ; 56 kDa (CK6) ; 55 kDa (CK7)

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.

Do you offer custom or private-label production of this type of product?

Yes, custom antibody development and private-label production services are available. Contact our sales team to discuss your target, timeline, and quantity requirements.

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