TNFS15 / VEGI (Vascular Endothelial Growth Inhibitor) (VEGI/2052R), CF740 conjugate, 0.1mg/mL — image 1 of 5

Product details

TNFS15 / VEGI (Vascular Endothelial Growth Inhibitor) (VEGI/2052R), CF740 conjugate, 0.1mg/mL

Catalog number BNC742052-500

Price for BNC742052-500

Size / count 1x 500 µL

About this product

VEGI is an anti-angiogenic cytokine that belongs to tumor necrosis factor superfamily, member 15 (TNFSF15) . This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It can activate NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. Reduced expression of VEGI has been reported as a marker of poor prognosis in breast cancer.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC742052-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: TNF ligand-related molecule 1 (TL1A) ; Tumor necrosis factor (ligand) superfamily member 15 (TNFSF15) ; Vascular endothelial growth inhibitor 192a; Vascular endothelial growth inhibitor (VEGI) ; VEGI192A
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: TNFSF15
Gene ID: 9966
NCBI Gene ID: 241382
UniProt: O95150
Swiss Prot: O95150
Host: Rabbit
Species Reactivity: Human
Reactivity: TNFS15|VEGI
Immunogen: Recombinant full-length human VEGI protein
Target Antigen: TNFS15 | VEGI
Clonality: Recombinant Monoclonal
Clone: VEGI/2052R
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Field of Research: Angiogenesis, Cytokines
Positive Control: Endothelial cells. Colon, intestine, placenta, lung, liver, kidney, pancreas, spleen and prostate.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% rBSA, 0.05% azide
Molecular Weight: 22 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG
Species: Oryctolagus cuniculus (domestic rabbit), Bos taurus (bovine)
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF740

Frequently Asked Questions

What is the catalog number for TNFS15 / VEGI (Vascular Endothelial Growth Inhibitor) (VEGI/2052R), CF740 conjugate, 0.1mg/mL?

The catalog number for TNFS15 / VEGI (Vascular Endothelial Growth Inhibitor) (VEGI/2052R), CF740 conjugate, 0.1mg/mL is BNC742052-500.

What sizes are available for TNFS15 / VEGI (Vascular Endothelial Growth Inhibitor) (VEGI/2052R), CF740 conjugate, 0.1mg/mL?

TNFS15 / VEGI (Vascular Endothelial Growth Inhibitor) (VEGI/2052R), CF740 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is TNFS15 / VEGI (Vascular Endothelial Growth Inhibitor) (VEGI/2052R), CF740 conjugate, 0.1mg/mL in stock?

TNFS15 / VEGI (Vascular Endothelial Growth Inhibitor) (VEGI/2052R), CF740 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures TNFS15 / VEGI (Vascular Endothelial Growth Inhibitor) (VEGI/2052R), CF740 conjugate, 0.1mg/mL?

TNFS15 / VEGI (Vascular Endothelial Growth Inhibitor) (VEGI/2052R), CF740 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for TNFS15 / VEGI (Vascular Endothelial Growth Inhibitor) (VEGI/2052R), CF740 conjugate, 0.1mg/mL?

Estimated delivery time for TNFS15 / VEGI (Vascular Endothelial Growth Inhibitor) (VEGI/2052R), CF740 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for TNFS15 / VEGI (Vascular Endothelial Growth Inhibitor) (VEGI/2052R), CF740 conjugate, 0.1mg/mL?

The safety data sheet for TNFS15 / VEGI (Vascular Endothelial Growth Inhibitor) (VEGI/2052R), CF740 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02a4061270361e10548d/msds/bnc742052-500.pdf.

What is TNFS15 / VEGI (Vascular Endothelial Growth Inhibitor) (VEGI/2052R), CF740 conjugate, 0.1mg/mL used for?

How do I reconstitute this lyophilized product?

Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.