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Product details

Alkaline Phosphatase (ALPL/597), Biotin conjugate, 0.1mg/mL

Catalog number BNCB0597-100

Price for BNCB0597-100

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Size / count 1x 100 µL

About this product

This antibody reacts with tissue non-specific alkaline phosphatase. There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific) . The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. The exact physiological function of the alkaline phosphatases is not known. A proposed function of this form of the enzyme is matrix mineralization; however, mice that lack a functional form of this enzyme show normal skeletal development. This enzyme has been linked directly to hypo-phosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects. The character of this disorder can vary, however, depending on the specific mutation since this determines age of onset and severity of symptoms. Alternatively spliced transcript variants, which encode the same protein, have been identified for this gene. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNCB0597-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Alkaline phosphatase tissue non-specific; Alkaline phosphatase liver/bone/kidney; Alkaline phosphatase biomineralization associated; TNAP; TNALP; ALPL
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
ALPP
Gene ID
248
NCBI Gene ID
284255; 333509; 370099; 75431
UniProt
P05186; P05187; P09923; P10696
Swiss Prot
P05186; P05187; P09923 & P10696
Host
Mouse
Species Reactivity
Cow, Human
Reactivity
Alkaline Phosphatase
Immunogen
Recombinant human ALP1 protein
Target Antigen
Alkaline Phosphatase
Clonality
Monoclonal
Clone
ALPL/597
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Field of Research
Developmental biology, Metabolism
Positive Control
Intestine
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
55 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
Biotin

Frequently Asked Questions

What is the catalog number for Alkaline Phosphatase (ALPL/597), Biotin conjugate, 0.1mg/mL?

The catalog number for Alkaline Phosphatase (ALPL/597), Biotin conjugate, 0.1mg/mL is BNCB0597-100.

What sizes are available for Alkaline Phosphatase (ALPL/597), Biotin conjugate, 0.1mg/mL?

Alkaline Phosphatase (ALPL/597), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Alkaline Phosphatase (ALPL/597), Biotin conjugate, 0.1mg/mL in stock?

Alkaline Phosphatase (ALPL/597), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Alkaline Phosphatase (ALPL/597), Biotin conjugate, 0.1mg/mL?

Alkaline Phosphatase (ALPL/597), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Alkaline Phosphatase (ALPL/597), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for Alkaline Phosphatase (ALPL/597), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Alkaline Phosphatase (ALPL/597), Biotin conjugate, 0.1mg/mL?

The safety data sheet for Alkaline Phosphatase (ALPL/597), Biotin conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Alkaline Phosphatase (ALPL/597), Biotin conjugate, 0.1mg/mL used for?

This antibody reacts with tissue non-specific alkaline phosphatase. There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific) . The first three are located together on chromosome 2, while the tissue non-spec

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

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