Bax (2D2), CF405S conjugate, 0.1mg/mL

Catalog number BNC040004-500

Price for BNC040004-500

Size / count 1x 500 µL

About this product

This antibody recognizes a protein of 21 kDa, identified as the Bax protein. This MAb is highly specific to Bax and shows no cross-reaction with Bcl-2 or Bcl-X protein. Bcl-2 blocks cell death following a variety of stimuli. Bax has extensive amino acid homology with Bcl-2 and it homodimerizes and forms heterodimers with Bcl-2. Overexpression of Bax accelerates apoptotic death induced by cytokine deprivation in an IL-3 dependent cell line, and Bax also counters the death repressor activity of Bcl-2. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC040004-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: BAX; Apoptosis regulator BAX; BCL2 associated X protein; Bcl-2-like protein 4
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: BAX
Gene ID: 581
NCBI Gene ID: 624291
UniProt: Q07812
Swiss Prot: Q07812
Host: Mouse
Species Reactivity: Human, Monkey
Reactivity: Bax
Immunogen: A synthetic peptide, aa 3-16 (Cys-GSGEQPRGGGPTSS) of human bax protein.
Target Antigen: Bax
Clonality: Monoclonal
Clone: 2D2
Type: Primary
Source: Animal
Origin: Animal
Applications: Flow, intracellular (verified) |IF (verified) |IHC, FFPE (verified)
Field of Research: Apoptosis, Cancer
Positive Control: Jurkat, K562, HL-60, or HeLa Cells. Reed-Sternberg cells in Hodgkin's lymphoma.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 21 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF405S

Frequently Asked Questions

What is the catalog number for Bax (2D2), CF405S conjugate, 0.1mg/mL?

The catalog number for Bax (2D2), CF405S conjugate, 0.1mg/mL is BNC040004-500.

What sizes are available for Bax (2D2), CF405S conjugate, 0.1mg/mL?

Bax (2D2), CF405S conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Bax (2D2), CF405S conjugate, 0.1mg/mL in stock?

Bax (2D2), CF405S conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Bax (2D2), CF405S conjugate, 0.1mg/mL?

Bax (2D2), CF405S conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Bax (2D2), CF405S conjugate, 0.1mg/mL?

Estimated delivery time for Bax (2D2), CF405S conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Bax (2D2), CF405S conjugate, 0.1mg/mL?

The safety data sheet for Bax (2D2), CF405S conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Bax (2D2), CF405S conjugate, 0.1mg/mL used for?

What is the purity of this recombinant protein?

Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.