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Product details

Bax (2D2), CF647 conjugate, 0.1mg/mL

Catalog number BNC470004-100

Price for BNC470004-100

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Size / count 1x 100 µL

About this product

This antibody recognizes a protein of 21 kDa, identified as the Bax protein. This MAb is highly specific to Bax and shows no cross-reaction with Bcl-2 or Bcl-X protein. Bcl-2 blocks cell death following a variety of stimuli. Bax has extensive amino acid homology with Bcl-2 and it homodimerizes and forms heterodimers with Bcl-2. Overexpression of Bax accelerates apoptotic death induced by cytokine deprivation in an IL-3 dependent cell line, and Bax also counters the death repressor activity of Bcl-2. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC470004-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
BAX; Apoptosis regulator BAX; BCL2 associated X protein; Bcl-2-like protein 4
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
BAX
Gene ID
581
NCBI Gene ID
624291
UniProt
Q07812
Swiss Prot
Q07812
Host
Mouse
Species Reactivity
Human, Monkey
Reactivity
Bax
Immunogen
A synthetic peptide, aa 3-16 (Cys-GSGEQPRGGGPTSS) of human bax protein.
Target Antigen
Bax
Clonality
Monoclonal
Clone
2D2
Type
Primary
Source
Animal
Origin
Animal
Applications
Flow, intracellular (verified) |IF (verified) |IHC, FFPE (verified)
Field of Research
Apoptosis, Cancer
Positive Control
Jurkat, K562, HL-60, or HeLa Cells. Reed-Sternberg cells in Hodgkin's lymphoma.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
21 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF647

Frequently Asked Questions

What is the catalog number for Bax (2D2), CF647 conjugate, 0.1mg/mL?

The catalog number for Bax (2D2), CF647 conjugate, 0.1mg/mL is BNC470004-100.

What sizes are available for Bax (2D2), CF647 conjugate, 0.1mg/mL?

Bax (2D2), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Bax (2D2), CF647 conjugate, 0.1mg/mL in stock?

Bax (2D2), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Bax (2D2), CF647 conjugate, 0.1mg/mL?

Bax (2D2), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Bax (2D2), CF647 conjugate, 0.1mg/mL?

Estimated delivery time for Bax (2D2), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Bax (2D2), CF647 conjugate, 0.1mg/mL?

The safety data sheet for Bax (2D2), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02b1061270361e109f7a/msds/bnc470004-100.pdf.

What is Bax (2D2), CF647 conjugate, 0.1mg/mL used for?

This antibody recognizes a protein of 21 kDa, identified as the Bax protein. This MAb is highly specific to Bax and shows no cross-reaction with Bcl-2 or Bcl-X protein. Bcl-2 blocks cell death following a variety of stimuli. Bax has extensive amino acid homology with Bcl-2 and it homodimerizes and f

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

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