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Product details

BCL-10 (BL10/411), 1mg/mL

Catalog number BNUM0411-50

Price for BNUM0411-50

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Size / count 1x 50 µL

About this product

B-cell lymphoma/leukemia 10 (BCL10) is a signaling protein that promotes apoptosis, pro-caspase-9 maturation, and activation of NF-kappa-B via NIK and IKK. BCL10 contains an N-terminal caspase recruitment domain (CARD), which is found in a number of apoptotic regulatory molecules. BCL10 is involved in the adaptive immune response, and may be an adapter protein between upstream TNFR1-TRADD-RIP complex and the downstream NIK-IKK-IKAP complex. A BCL10 translocation is recurrent in low-grade mucosa-associated lymphoid tissue (MALT lymphoma) Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNUM0411-50
Size / count
1x 50 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
BCL10; BCL-10; B-cell CLL/lymphoma 10; B-cell leukemia/lymphoma 10
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
BCL10
Gene ID
8915
NCBI Gene ID
193516
UniProt
O95999
Swiss Prot
O95999
Host
Mouse
Species Reactivity
Human
Reactivity
BCL10
Immunogen
Human BCL10 recombinant protein (epitope aa122-168)
Target Antigen
BCL10
Clonality
Monoclonal
Clone
BL10/411
Type
Primary
Source
Animal
Origin
Animal
Applications
Flow, intracellular (verified) |IHC, FFPE (verified) |WB (verified)
Field of Research
Apoptosis, Cancer, Immunology, Signal transduction
Positive Control
HepG2 cells or Lymphoma.
Stability
2 years
Concentration
1 mg/mL
Buffer
PBS, no BSA, no azide
Molecular Weight
33 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse)
Classification
PBS, no BSA, no sodium azide (CAS 26628-22-8)
Conjugate
Purified, BSA-free

Frequently Asked Questions

What is the catalog number for BCL-10 (BL10/411), 1mg/mL?

The catalog number for BCL-10 (BL10/411), 1mg/mL is BNUM0411-50.

What sizes are available for BCL-10 (BL10/411), 1mg/mL?

BCL-10 (BL10/411), 1mg/mL is available in the following size(s): 1x 50 µL.

Is BCL-10 (BL10/411), 1mg/mL in stock?

BCL-10 (BL10/411), 1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures BCL-10 (BL10/411), 1mg/mL?

BCL-10 (BL10/411), 1mg/mL is manufactured by Biotium.

What is the estimated delivery time for BCL-10 (BL10/411), 1mg/mL?

Estimated delivery time for BCL-10 (BL10/411), 1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for BCL-10 (BL10/411), 1mg/mL?

The safety data sheet for BCL-10 (BL10/411), 1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is BCL-10 (BL10/411), 1mg/mL used for?

B-cell lymphoma/leukemia 10 (BCL10) is a signaling protein that promotes apoptosis, pro-caspase-9 maturation, and activation of NF-kappa-B via NIK and IKK. BCL10 contains an N-terminal caspase recruitment domain (CARD), which is found in a number of apoptotic regulatory molecules. BCL10 is involved

What is the immunogen used to generate this antibody?

Immunogen or antigen details used to raise this antibody are listed on the product datasheet under immunogen information.

What is the recommended positive control for this assay?

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

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