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Product details

BCL-10 (BL10/411), Biotin conjugate, 0.1mg/mL

Catalog number BNCB0411-500

Price for BNCB0411-500

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Size / count 1x 500 µL

About this product

B-cell lymphoma/leukemia 10 (BCL10) is a signaling protein that promotes apoptosis, pro-caspase-9 maturation, and activation of NF-kappa-B via NIK and IKK. BCL10 contains an N-terminal caspase recruitment domain (CARD), which is found in a number of apoptotic regulatory molecules. BCL10 is involved in the adaptive immune response, and may be an adapter protein between upstream TNFR1-TRADD-RIP complex and the downstream NIK-IKK-IKAP complex. A BCL10 translocation is recurrent in low-grade mucosa-associated lymphoid tissue (MALT lymphoma) Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNCB0411-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
BCL10; BCL-10; B-cell CLL/lymphoma 10; B-cell leukemia/lymphoma 10
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
BCL10
Gene ID
8915
NCBI Gene ID
193516
UniProt
O95999
Swiss Prot
O95999
Host
Mouse
Species Reactivity
Human
Reactivity
BCL10
Immunogen
Human BCL10 recombinant protein (epitope aa122-168)
Target Antigen
BCL10
Clonality
Monoclonal
Clone
BL10/411
Type
Primary
Source
Animal
Origin
Animal
Applications
Flow, intracellular (verified) |IHC, FFPE (verified) |WB (verified)
Field of Research
Apoptosis, Cancer, Immunology, Signal transduction
Positive Control
HepG2 cells or Lymphoma.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
33 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
Biotin

Frequently Asked Questions

What is the catalog number for BCL-10 (BL10/411), Biotin conjugate, 0.1mg/mL?

The catalog number for BCL-10 (BL10/411), Biotin conjugate, 0.1mg/mL is BNCB0411-500.

What sizes are available for BCL-10 (BL10/411), Biotin conjugate, 0.1mg/mL?

BCL-10 (BL10/411), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is BCL-10 (BL10/411), Biotin conjugate, 0.1mg/mL in stock?

BCL-10 (BL10/411), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures BCL-10 (BL10/411), Biotin conjugate, 0.1mg/mL?

BCL-10 (BL10/411), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for BCL-10 (BL10/411), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for BCL-10 (BL10/411), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for BCL-10 (BL10/411), Biotin conjugate, 0.1mg/mL?

The safety data sheet for BCL-10 (BL10/411), Biotin conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029a061270361e101b9f/msds/bncb0411-500.pdf.

What is BCL-10 (BL10/411), Biotin conjugate, 0.1mg/mL used for?

B-cell lymphoma/leukemia 10 (BCL10) is a signaling protein that promotes apoptosis, pro-caspase-9 maturation, and activation of NF-kappa-B via NIK and IKK. BCL10 contains an N-terminal caspase recruitment domain (CARD), which is found in a number of apoptotic regulatory molecules. BCL10 is involved

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

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