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Product details

Thrombomodulin / CD141 (Endothelial Cell Marker) (THBD/1782), CF740 conjugate, 0.1mg/mL

Catalog number BNC741782-500

Price for BNC741782-500

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Size / count 1x 500 µL

About this product

This antibody recognizes a protein of 75 kDa, identified as Thrombomodulin. Thrombomodulin is a transmembrane glycoprotein with natural anticoagulant properties. It is normally expressed by a restricted number of cells, such as endothelial and mesothelial cells. In addition, synovial lining and syncytio-trophoblasts of placenta also express thrombomodulin. This protein is present in almost all of benign vascular tumors and majority of malignant vascular tumors (Kaposi's sarcoma, angiosarcoma, and epithelioid hemangioendothelioma) . Hence, anti-thrombomodulin serves as a sensitive marker for lymphatic endothelial cells and their tumors. Recently, thrombomodulin antibody has been used for mesothelial cells and malignant mesotheliomas.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC741782-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
AHUS6; BDCA3; CD141; Fetomodulin; Thbd; THPH12; THRM; Thrombomodulin (TM)
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
THBD
Gene ID
7056
NCBI Gene ID
2030
UniProt
P07204
Swiss Prot
P07204
Host
Mouse
Species Reactivity
Human
Reactivity
CD141|Thrombomodulin
Immunogen
Recombinant human Thrombomodulin protein fragment (aa69-194) (exact sequence is proprietary)
Target Antigen
CD141 | Thrombomodulin
Clonality
Monoclonal
Clone
THBD/1782
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Field of Research
Cancer
Positive Control
THP1 Cells. Placenta, Angiosarcoma, Bladder or Cervical Carcinoma
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% rBSA, 0.05% azide
Molecular Weight
100 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2a, kappa
Species
Mus musculus (mouse), Bos taurus (bovine)
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF740

Frequently Asked Questions

What is the catalog number for Thrombomodulin / CD141 (Endothelial Cell Marker) (THBD/1782), CF740 conjugate, 0.1mg/mL?

The catalog number for Thrombomodulin / CD141 (Endothelial Cell Marker) (THBD/1782), CF740 conjugate, 0.1mg/mL is BNC741782-500.

What sizes are available for Thrombomodulin / CD141 (Endothelial Cell Marker) (THBD/1782), CF740 conjugate, 0.1mg/mL?

Thrombomodulin / CD141 (Endothelial Cell Marker) (THBD/1782), CF740 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Thrombomodulin / CD141 (Endothelial Cell Marker) (THBD/1782), CF740 conjugate, 0.1mg/mL in stock?

Thrombomodulin / CD141 (Endothelial Cell Marker) (THBD/1782), CF740 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Thrombomodulin / CD141 (Endothelial Cell Marker) (THBD/1782), CF740 conjugate, 0.1mg/mL?

Thrombomodulin / CD141 (Endothelial Cell Marker) (THBD/1782), CF740 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Thrombomodulin / CD141 (Endothelial Cell Marker) (THBD/1782), CF740 conjugate, 0.1mg/mL?

Estimated delivery time for Thrombomodulin / CD141 (Endothelial Cell Marker) (THBD/1782), CF740 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Thrombomodulin / CD141 (Endothelial Cell Marker) (THBD/1782), CF740 conjugate, 0.1mg/mL?

The safety data sheet for Thrombomodulin / CD141 (Endothelial Cell Marker) (THBD/1782), CF740 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02a9061270361e106d51/msds/bnc741782-500.pdf.

What is Thrombomodulin / CD141 (Endothelial Cell Marker) (THBD/1782), CF740 conjugate, 0.1mg/mL used for?

This antibody recognizes a protein of 75 kDa, identified as Thrombomodulin. Thrombomodulin is a transmembrane glycoprotein with natural anticoagulant properties. It is normally expressed by a restricted number of cells, such as endothelial and mesothelial cells. In addition, synovial lining and sync

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

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