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Product details
Catalog number BNUM0850-50
Price for BNUM0850-50
Size / count 1x 50 µL
Bcl-6 is a transcriptional repressor mainly required for germinal center (GC) formation and antibody affinity maturation which has different mechanisms of action specific to the lineage and biological functions. It forms complexes with different corepressors and histone deacetylases to repress the transcriptional expression of different subsets of target genes. Bcl-6 allows GC B-cells to proliferate very rapidly in response to T-cell dependent antigens and tolerate the physiological DNA breaks required for immunglobulin class switch recombination and somatic hypermutation without inducing a p53/TP53-dependent apoptotic response. Antibodies to Bcl-6 are helpful in a number of diagnostic settings, for example in the differential diagnosis of small B-cell lymphoma, and in distinguishing classical Hodgkin lymphoma from nodular lymphocyte predominant Hodgkin lymphoma (NLPHL) .Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for Bcl-6 (BCL6/850), 1mg/mL is BNUM0850-50.
Bcl-6 (BCL6/850), 1mg/mL is available in the following size(s): 1x 50 µL.
Bcl-6 (BCL6/850), 1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
Bcl-6 (BCL6/850), 1mg/mL is manufactured by Biotium.
Estimated delivery time for Bcl-6 (BCL6/850), 1mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for Bcl-6 (BCL6/850), 1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029d061270361e102b80/msds/bnum0850-50.pdf.
Bcl-6 is a transcriptional repressor mainly required for germinal center (GC) formation and antibody affinity maturation which has different mechanisms of action specific to the lineage and biological functions. It forms complexes with different corepressors and histone deacetylases to repress the t
Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.
Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.
Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.
