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Product details

Beta Catenin (p120) (Rabbit PAb), Biotin conjugate, 0.1mg/mL

Catalog number BNCB0376-100

Price for BNCB0376-100

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Size / count 1x 100 µL

About this product

Beta-catenin associates with the cytoplasmic portion of E-cadherin. The catenin/cadherin complexes play an important role mediating cellular adhesion, including adherens junctions. Beta-catenin is involved in the Wnt signaling pathway as well as other signaling pathways, and is also found in complexes with many different proteins including the tumor suppressor protein APC. Defects in beta-catenin are associated with colorectal cancer, as well as many other cancer types. Beta-catenin is normally localized to the cell membrane, but can translocate to the nucleus in response to certain cell signaling. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNCB0376-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Beta-catenin; Catenin beta-1; Catenin (Cadherin associated protein), beta 1; CTNNB
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
CTNNB1
Gene ID
1499
NCBI Gene ID
476018
UniProt
P35222
Swiss Prot
P35222
Host
Rabbit
Species Reactivity
Human, Mouse
Reactivity
Beta-catenin|Catenin, Beta
Immunogen
A synthetic peptide from the middle of beta-Catenin (p120) protein
Target Antigen
Beta-catenin | Catenin, Beta
Clonality
Polyclonal
Clone
PAb
Type
Primary
Source
Animal
Origin
Animal
Applications
Flow, intracellular (verified) |IHC, FFPE (verified) |WB (verified)
Field of Research
Cancer, Cell adhesion, Developmental biology, Signal transduction
Positive Control
HeLa or MCF-7 cells. Breast carcinoma
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
92 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG, kappa
Species
Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
Biotin

Frequently Asked Questions

What is the catalog number for Beta Catenin (p120) (Rabbit PAb), Biotin conjugate, 0.1mg/mL?

The catalog number for Beta Catenin (p120) (Rabbit PAb), Biotin conjugate, 0.1mg/mL is BNCB0376-100.

What sizes are available for Beta Catenin (p120) (Rabbit PAb), Biotin conjugate, 0.1mg/mL?

Beta Catenin (p120) (Rabbit PAb), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Beta Catenin (p120) (Rabbit PAb), Biotin conjugate, 0.1mg/mL in stock?

Beta Catenin (p120) (Rabbit PAb), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Beta Catenin (p120) (Rabbit PAb), Biotin conjugate, 0.1mg/mL?

Beta Catenin (p120) (Rabbit PAb), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Beta Catenin (p120) (Rabbit PAb), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for Beta Catenin (p120) (Rabbit PAb), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Beta Catenin (p120) (Rabbit PAb), Biotin conjugate, 0.1mg/mL?

The safety data sheet for Beta Catenin (p120) (Rabbit PAb), Biotin conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Beta Catenin (p120) (Rabbit PAb), Biotin conjugate, 0.1mg/mL used for?

Beta-catenin associates with the cytoplasmic portion of E-cadherin. The catenin/cadherin complexes play an important role mediating cellular adhesion, including adherens junctions. Beta-catenin is involved in the Wnt signaling pathway as well as other signaling pathways, and is also found in complex

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.

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