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Product details

Beta Catenin (p120) (Rabbit PAb), CF647 conjugate, 0.1mg/mL

Catalog number BNC470376-500

Price for BNC470376-500

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Size / count 1x 500 µL

About this product

Beta-catenin associates with the cytoplasmic portion of E-cadherin. The catenin/cadherin complexes play an important role mediating cellular adhesion, including adherens junctions. Beta-catenin is involved in the Wnt signaling pathway as well as other signaling pathways, and is also found in complexes with many different proteins including the tumor suppressor protein APC. Defects in beta-catenin are associated with colorectal cancer, as well as many other cancer types. Beta-catenin is normally localized to the cell membrane, but can translocate to the nucleus in response to certain cell signaling. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC470376-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Beta-catenin; Catenin beta-1; Catenin (Cadherin associated protein), beta 1; CTNNB
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
CTNNB1
Gene ID
1499
NCBI Gene ID
476018
UniProt
P35222
Swiss Prot
P35222
Host
Rabbit
Species Reactivity
Human, Mouse
Reactivity
Beta-catenin|Catenin, Beta
Immunogen
A synthetic peptide from the middle of beta-Catenin (p120) protein
Target Antigen
Beta-catenin | Catenin, Beta
Clonality
Polyclonal
Clone
PAb
Type
Primary
Source
Animal
Origin
Animal
Applications
Flow, intracellular (verified) |IHC, FFPE (verified) |WB (verified)
Field of Research
Cancer, Cell adhesion, Developmental biology, Signal transduction
Positive Control
HeLa or MCF-7 cells. Breast carcinoma
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
92 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG, kappa
Species
Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF647

Frequently Asked Questions

What is the catalog number for Beta Catenin (p120) (Rabbit PAb), CF647 conjugate, 0.1mg/mL?

The catalog number for Beta Catenin (p120) (Rabbit PAb), CF647 conjugate, 0.1mg/mL is BNC470376-500.

What sizes are available for Beta Catenin (p120) (Rabbit PAb), CF647 conjugate, 0.1mg/mL?

Beta Catenin (p120) (Rabbit PAb), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Beta Catenin (p120) (Rabbit PAb), CF647 conjugate, 0.1mg/mL in stock?

Beta Catenin (p120) (Rabbit PAb), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Beta Catenin (p120) (Rabbit PAb), CF647 conjugate, 0.1mg/mL?

Beta Catenin (p120) (Rabbit PAb), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Beta Catenin (p120) (Rabbit PAb), CF647 conjugate, 0.1mg/mL?

Estimated delivery time for Beta Catenin (p120) (Rabbit PAb), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Beta Catenin (p120) (Rabbit PAb), CF647 conjugate, 0.1mg/mL?

The safety data sheet for Beta Catenin (p120) (Rabbit PAb), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02a3061270361e104c94/msds/bnc470376-500.pdf.

What is Beta Catenin (p120) (Rabbit PAb), CF647 conjugate, 0.1mg/mL used for?

Beta-catenin associates with the cytoplasmic portion of E-cadherin. The catenin/cadherin complexes play an important role mediating cellular adhesion, including adherens junctions. Beta-catenin is involved in the Wnt signaling pathway as well as other signaling pathways, and is also found in complex

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

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