Ferritin, Heavy Chain (FTH) (Microglia Marker) (FTH/2081), CF740 conjugate, 0.1mg/mL

Catalog number BNC742081-100

Price for BNC742081-100

Size / count 1x 100 µL

About this product

Mammalian ferritins consist of 24 subunits made up of 2 types of poly-peptide chains, ferritin heavy chain and ferritin light chain, which each have unique functions. Ferritin heavy chains catalyze the first step in iron storage, the oxidationof FeI (II), whereas ferritin light chains promote the nucleation of ferrihydrite, enabling storage of Fe (III) . The most prominent role of mammalian ferritins is to provide iron-buffering capacity to cells. In addition to iron buffering, heavy chain ferritin is also involved in the regulation of thymidine biosynthesis via increased expression of cytoplasmic serine hydroxymethyltransferase, which is a limiting factor in thymidylate synthesis in MCF-7 cells. Light chain ferritin is involved in cataracts by at least two mechanisms: hereditary hyperferritinemia cataract syndrome, in which light chain ferritin is overexpressed; and oxidative stress, an important factor in the development of aging-related cataracts. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC742081-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Apoferritin; Cell proliferation-inducing gene 15 protein; Ferritin H subunit; Ferritin heavy chain; FHC; FRIH; FTH1; FTHL6; Iron overload autosomal dominant; PIG15; Placenta immunoregulatory factor; Proliferation inducing gene 15 protein (PLIF)
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: FTH1
Gene ID: 2495
NCBI Gene ID: 524910; 645560
UniProt: P02794
Swiss Prot: P02794
Host: Mouse
Species Reactivity: Human
Reactivity: Ferritin, Heavy Chain
Immunogen: Recombinant human FTH1 protein fragment (around aa 58-180) (exact sequence is proprietary)
Target Antigen: Ferritin, Heavy Chain
Clonality: Monoclonal
Clone: FTH/2081
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified) |WB (verified)
Positive Control: HepG2, HeLa, HL-60 or 293T cells. Pancreas, Liver, Cerebellum or Testis.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% rBSA, 0.05% azide
Molecular Weight: 21 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2a, kappa
Species: Mus musculus (mouse), Bos taurus (bovine)
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF740

Frequently Asked Questions

What is the catalog number for Ferritin, Heavy Chain (FTH) (Microglia Marker) (FTH/2081), CF740 conjugate, 0.1mg/mL?

The catalog number for Ferritin, Heavy Chain (FTH) (Microglia Marker) (FTH/2081), CF740 conjugate, 0.1mg/mL is BNC742081-100.

What sizes are available for Ferritin, Heavy Chain (FTH) (Microglia Marker) (FTH/2081), CF740 conjugate, 0.1mg/mL?

Ferritin, Heavy Chain (FTH) (Microglia Marker) (FTH/2081), CF740 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Ferritin, Heavy Chain (FTH) (Microglia Marker) (FTH/2081), CF740 conjugate, 0.1mg/mL in stock?

Ferritin, Heavy Chain (FTH) (Microglia Marker) (FTH/2081), CF740 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Ferritin, Heavy Chain (FTH) (Microglia Marker) (FTH/2081), CF740 conjugate, 0.1mg/mL?

Ferritin, Heavy Chain (FTH) (Microglia Marker) (FTH/2081), CF740 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Ferritin, Heavy Chain (FTH) (Microglia Marker) (FTH/2081), CF740 conjugate, 0.1mg/mL?

Estimated delivery time for Ferritin, Heavy Chain (FTH) (Microglia Marker) (FTH/2081), CF740 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Ferritin, Heavy Chain (FTH) (Microglia Marker) (FTH/2081), CF740 conjugate, 0.1mg/mL?

The safety data sheet for Ferritin, Heavy Chain (FTH) (Microglia Marker) (FTH/2081), CF740 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02ab061270361e107886/msds/bnc742081-100.pdf.

What is Ferritin, Heavy Chain (FTH) (Microglia Marker) (FTH/2081), CF740 conjugate, 0.1mg/mL used for?

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.