Caldesmon, HMW (h-Caldesmon) (CALD1/820 + h-CALD), CF647 conjugate, 0.1mg/mL

Catalog number BNC470821-500

Price for BNC470821-500

Size / count 1x 500 µL

About this product

Caldesmon HMW is the high molecular weight variant of Caldesmon. Two closely related variants of human caldesmon have been identified which are different in their electrophoretic mobility and cellular distribution. The h-caldesmon variant (120-150 kDa) is predominantly expressed in smooth muscle whereas l-caldesmon (70-80 kDa) is found in non- muscle tissue and cells. Neither of the two variants has been detected in skeletal muscle. This MAb recognizes only the 150 kDa variant (h-caldesmon) in Western blots of human aortic media extracts and is unreactive with fibroblast extracts from cultivated human foreskin. Caldesmon is a developmentally regulated protein involved in smooth muscle and non-muscle contraction.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC470821-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Caldesmon; Caldesmon 1; Caldesmon 1 Isoform 1; CDM; HCAD
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: CALD1
Gene ID: 800
NCBI Gene ID: 490203
UniProt: Q05682
Swiss Prot: Q05682
Host: Mouse
Species Reactivity: Human
Reactivity: Caldesmon, HMW
Immunogen: Recombinant full-length human CALD1 protein (CALD1/820) ; Crude human uterus extract (h-CALD)
Target Antigen: Caldesmon, HMW
Clonality: Monoclonal
Clone: CALD1/820 h-CALD
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Field of Research: Cytoskeleton
Positive Control: Uterus, Blood vessels in all tissues, smooth muscle or leiomyosarcoma
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 150 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG' s
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF647

Frequently Asked Questions

What is the catalog number for Caldesmon, HMW (h-Caldesmon) (CALD1/820 + h-CALD), CF647 conjugate, 0.1mg/mL?

The catalog number for Caldesmon, HMW (h-Caldesmon) (CALD1/820 + h-CALD), CF647 conjugate, 0.1mg/mL is BNC470821-500.

What sizes are available for Caldesmon, HMW (h-Caldesmon) (CALD1/820 + h-CALD), CF647 conjugate, 0.1mg/mL?

Caldesmon, HMW (h-Caldesmon) (CALD1/820 + h-CALD), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Caldesmon, HMW (h-Caldesmon) (CALD1/820 + h-CALD), CF647 conjugate, 0.1mg/mL in stock?

Caldesmon, HMW (h-Caldesmon) (CALD1/820 + h-CALD), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Caldesmon, HMW (h-Caldesmon) (CALD1/820 + h-CALD), CF647 conjugate, 0.1mg/mL?

Caldesmon, HMW (h-Caldesmon) (CALD1/820 + h-CALD), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Caldesmon, HMW (h-Caldesmon) (CALD1/820 + h-CALD), CF647 conjugate, 0.1mg/mL?

Estimated delivery time for Caldesmon, HMW (h-Caldesmon) (CALD1/820 + h-CALD), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Caldesmon, HMW (h-Caldesmon) (CALD1/820 + h-CALD), CF647 conjugate, 0.1mg/mL?

The safety data sheet for Caldesmon, HMW (h-Caldesmon) (CALD1/820 + h-CALD), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02b1061270361e109dd4/msds/bnc470821-500.pdf.

What is Caldesmon, HMW (h-Caldesmon) (CALD1/820 + h-CALD), CF647 conjugate, 0.1mg/mL used for?

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.