Langerin / CD207 (Marker of Langerhans Cells) (LGRN/1821), CF740 conjugate, 0.1mg/mL

Catalog number BNC741821-100

Price for BNC741821-100

Size / count 1x 100 µL

About this product

Langerhans cells (LCs) are a subset of immature dendritic cells (DCs) that specifically localize in the epidermis and other mucosal epithelia. Epidermal LCs possess strong immuno-stimulatory capacity and play a central role in the initiation and regulation of immune responses. Langerin (CD207) is a Ca2 -dependent, C-type lectin domain containing, type II transmembrane protein that induces epidermal LCs to differentiate into Birbeck granules (BG) . BGs are organelles with superimposing and zippering membranes that influence proper class I type antigen presentation to the circulating T cells. Human spleen, lymph node, thymus, liver, lung and heart express Langerin protein. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC741821-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: C-type lectin domain family 4 member K; CD207; CLEC4K; Langerhans cell specific c type lectin; Langerin
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: CD207
Gene ID: 50489
NCBI Gene ID: 199731
UniProt: Q9UJ71
Swiss Prot: Q9UJ71
Host: Mouse
Species Reactivity: Human
Reactivity: CD207|Langerin
Immunogen: Recombinant fragment (around aa74-213) of human Langerin protein (exact sequence is proprietary)
Target Antigen: CD207 | Langerin
Clonality: Monoclonal
Clone: LGRN/1821
Type: Primary
Source: Animal
Origin: Animal
Positive Control: HeLa or A549 cells (WB).
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% rBSA, 0.05% azide
Molecular Weight: 48 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2a, kappa
Species: Mus musculus (mouse), Bos taurus (bovine)
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF740

Frequently Asked Questions

What is the catalog number for Langerin / CD207 (Marker of Langerhans Cells) (LGRN/1821), CF740 conjugate, 0.1mg/mL?

The catalog number for Langerin / CD207 (Marker of Langerhans Cells) (LGRN/1821), CF740 conjugate, 0.1mg/mL is BNC741821-100.

What sizes are available for Langerin / CD207 (Marker of Langerhans Cells) (LGRN/1821), CF740 conjugate, 0.1mg/mL?

Langerin / CD207 (Marker of Langerhans Cells) (LGRN/1821), CF740 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Langerin / CD207 (Marker of Langerhans Cells) (LGRN/1821), CF740 conjugate, 0.1mg/mL in stock?

Langerin / CD207 (Marker of Langerhans Cells) (LGRN/1821), CF740 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Langerin / CD207 (Marker of Langerhans Cells) (LGRN/1821), CF740 conjugate, 0.1mg/mL?

Langerin / CD207 (Marker of Langerhans Cells) (LGRN/1821), CF740 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Langerin / CD207 (Marker of Langerhans Cells) (LGRN/1821), CF740 conjugate, 0.1mg/mL?

Estimated delivery time for Langerin / CD207 (Marker of Langerhans Cells) (LGRN/1821), CF740 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Langerin / CD207 (Marker of Langerhans Cells) (LGRN/1821), CF740 conjugate, 0.1mg/mL?

The safety data sheet for Langerin / CD207 (Marker of Langerhans Cells) (LGRN/1821), CF740 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02a3061270361e104f38/msds/bnc741821-100.pdf.

What is Langerin / CD207 (Marker of Langerhans Cells) (LGRN/1821), CF740 conjugate, 0.1mg/mL used for?

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.

Do you offer custom or private-label production of this type of product?

Yes, custom antibody development and private-label production services are available. Contact our sales team to discuss your target, timeline, and quantity requirements.