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Product details

CD45 / LCA (B-Cell Marker) (rPTPRC/1460), CF740 conjugate, 0.1mg/mL

Catalog number BNC742066-100

Price for BNC742066-100

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Size / count 1x 100 µL

About this product

CD45R, also designated CD45 and PTPRC, has been identified as a transmembrane glycoprotein, broadly expressed among hematopoietic cells. Multiple isoforms of CD45R are distributed throughout the immune system according to cell type. These isoforms arise because of alternative splicing of exons 4, 5, and 6. The corresponding protein domains are characterized by the binding of monoclonal antibodies specific for CD45RA (exon 4), CD45RB (exon 5), CD45RC (exon 6) and CD45RO (exons 4 to 6 spliced out) . The variation in these isoforms is localized to the extracellular domain of CD45R, while the intracellular domain is conserved. CD45R functions as a phosphor-tyrosine phosphatase. Antibody to CD45 is useful in differential diagnosis of lymphoid tumors from non-hematopoietic undifferentiated neoplasms. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC742066-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
B220; CD45R; GP180; Leukocyte common antigen (LCA) ; Loc; Ly-5; Lyt-4; Protein tyrosine phosphatase receptor type C (PTPRC) ; Receptor-type tyrosine-protein phosphatase C; T200 glycoprotein
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
PTPRC
Gene ID
5788
NCBI Gene ID
654514
UniProt
P08575
Swiss Prot
P08575
Host
Mouse
Species Reactivity
Human
Reactivity
CD45|LCA
Immunogen
Human recombinant full-length CD45 protein
Target Antigen
CD45 | LCA
Clonality
Recombinant Monoclonal
Clone
RPTPRC/1460
Type
Primary
Source
Animal
Origin
Animal
Applications
Flow (verified) |IHC, FFPE (verified) |WB (verified)
Field of Research
Immunology, Signal transduction
Positive Control
Ramos, U-698 or GA-10 cells. Tonsil and Spleen.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% rBSA, 0.05% azide
Molecular Weight
180-220 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), Bos taurus (bovine)
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF740

Frequently Asked Questions

What is the catalog number for CD45 / LCA (B-Cell Marker) (rPTPRC/1460), CF740 conjugate, 0.1mg/mL?

The catalog number for CD45 / LCA (B-Cell Marker) (rPTPRC/1460), CF740 conjugate, 0.1mg/mL is BNC742066-100.

What sizes are available for CD45 / LCA (B-Cell Marker) (rPTPRC/1460), CF740 conjugate, 0.1mg/mL?

CD45 / LCA (B-Cell Marker) (rPTPRC/1460), CF740 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is CD45 / LCA (B-Cell Marker) (rPTPRC/1460), CF740 conjugate, 0.1mg/mL in stock?

CD45 / LCA (B-Cell Marker) (rPTPRC/1460), CF740 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD45 / LCA (B-Cell Marker) (rPTPRC/1460), CF740 conjugate, 0.1mg/mL?

CD45 / LCA (B-Cell Marker) (rPTPRC/1460), CF740 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for CD45 / LCA (B-Cell Marker) (rPTPRC/1460), CF740 conjugate, 0.1mg/mL?

Estimated delivery time for CD45 / LCA (B-Cell Marker) (rPTPRC/1460), CF740 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD45 / LCA (B-Cell Marker) (rPTPRC/1460), CF740 conjugate, 0.1mg/mL?

The safety data sheet for CD45 / LCA (B-Cell Marker) (rPTPRC/1460), CF740 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02b8061270361e10c368/msds/bnc742066-100.pdf.

What is CD45 / LCA (B-Cell Marker) (rPTPRC/1460), CF740 conjugate, 0.1mg/mL used for?

CD45R, also designated CD45 and PTPRC, has been identified as a transmembrane glycoprotein, broadly expressed among hematopoietic cells. Multiple isoforms of CD45R are distributed throughout the immune system according to cell type. These isoforms arise because of alternative splicing of exons 4, 5,

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

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