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Product details

CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) (rCR2/1952), CF740 conjugate, 0.1mg/mL

Catalog number BNC743789-100

Price for BNC743789-100

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Size / count 1x 100 µL

About this product

Recognizes a protein of 140 kDa, which is identified as the complement receptor 2 (CR2) /CD21. This protein is expressed strongly on mature B cells, follicular dendritic cells and weakly on immature thymocytes and T lymphocytes. In B-cell ontogeny, CD21 appears after the pre-B-stage, is maintained during peripheral B-cell development and is lost upon terminal differentiation into plasma cells. CD21 expression is also gradually lost after stimulation of B cells in vitro. CD21 functions as receptor for C3d, C3dg and iC3b Complement components, for EBV and for IFNalpha. CD21 binds to CD23 and associates with CD19, CD81 and Leu13 to form a large signal-transduction complex involved in B cell activation. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC743789-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
CD21; Complement C3d receptor (C3DR) ; Complement Receptor type 2 (CR2) ; CVID7; EBV receptor; EBV-R; Epstein-Barr virus receptor; EVBR; SLEB9
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
CR2
Gene ID
1380
NCBI Gene ID
445757
UniProt
P20023
Swiss Prot
P20023
Host
Mouse
Species Reactivity
Human
Reactivity
CD21
Immunogen
Recombinant fragment (around aa 44-196) of human CR2 (CD21) protein (exact sequence is proprietary)
Target Antigen
CD21
Clonality
Recombinant Monoclonal
Clone
RCR2/1952
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Positive Control
WEHI-231 cells. Human tonsil (IHC).
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% rBSA, 0.05% azide
Molecular Weight
140 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF740

Frequently Asked Questions

What is the catalog number for CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) (rCR2/1952), CF740 conjugate, 0.1mg/mL?

The catalog number for CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) (rCR2/1952), CF740 conjugate, 0.1mg/mL is BNC743789-100.

What sizes are available for CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) (rCR2/1952), CF740 conjugate, 0.1mg/mL?

CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) (rCR2/1952), CF740 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) (rCR2/1952), CF740 conjugate, 0.1mg/mL in stock?

CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) (rCR2/1952), CF740 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) (rCR2/1952), CF740 conjugate, 0.1mg/mL?

CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) (rCR2/1952), CF740 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) (rCR2/1952), CF740 conjugate, 0.1mg/mL?

Estimated delivery time for CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) (rCR2/1952), CF740 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) (rCR2/1952), CF740 conjugate, 0.1mg/mL?

The safety data sheet for CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) (rCR2/1952), CF740 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0299061270361e100f9b/msds/bnc743789-100.pdf.

What is CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) (rCR2/1952), CF740 conjugate, 0.1mg/mL used for?

Recognizes a protein of 140 kDa, which is identified as the complement receptor 2 (CR2) /CD21. This protein is expressed strongly on mature B cells, follicular dendritic cells and weakly on immature thymocytes and T lymphocytes. In B-cell ontogeny, CD21 appears after the pre-B-stage, is maintained d

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

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